A Terahertz Electromagnetically Induced Transparency-Like Metamaterial for Biosensing

Nourinovin, Shohreh; Alomainy, Akram

doi:10.23919/eucap51087.2021.9411483

Cited by 9 publications

(5 citation statements)

References 24 publications

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“…Morever, the sensor is angularly independent for angles up to θ = 90 o with no degeneration in the absorptivity at 1.9612 THz which is considered beneficial results over those reported by (Cheng et al 2018;Veeraselvam et al 2021a). The peak sensitivity of the proposed sensor is 968 GHz/RIU and 264 GHz/RIU at 1.9656 THz and 3.3692 THz, respectively which is greater than the sensitivity achieved in some relevant literatures (Nourinovin and Alomainy 2021;Yan et al 2019;Zhang et al 2018). The proposed biosensor was analyzed and compared with the traditional sensors of a single resonant peak.…”

Section: Effect Of Bio-med Samplesmentioning

confidence: 85%

“…Cheng et al (2018) achieved Jerusalem cross apertures' metamaterial absorber based on the strongly confined spoof surface plasmon polaritons resonance mode in THz regime for different subtypes and protein concentration biosensing of AI viruses. State-of-the-art research involves the development of THz metamaterials with split-ring resonators characteristics (Geng et al 2022;Islam et al 2022;Nourinovin and Alomainy 2021). The authors proposed a metamaterialstructure that exhibits electromagnetically induced transparency-like (EIT-like) Fano resonance.…”

Section: Introductionmentioning

confidence: 99%

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Design and optimization of highly sensitive multi-band terahertz metamaterial biosensor for coronaviruses detection

2023

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This study presents the design and characterization of a highly Q-Factor and ultrasensitive THz refractive-index-based metamaterial biosensor for detecting coronaviruses at electronic infusion device (EID) concentrations $$0.01$$ 0.01 and $$1000$$ 1000 . The proposed biosensor is constructed using a gold plane perforated by a star shape. Moreover, the developed structure is polarization insensitive due to the rotatory symmetry and is angularly stable up to 90°. The proposed biosensor achieves near-perfect absorption at $$1.9656$$ 1.9656 THz and $$3.3692$$ 3.3692 THz. The full width at half-maximum is $$5.276\%$$ 5.276 % and $$0.641\%$$ 0.641 % comparative to the absorption frequency. In addition, the estimated free space absorptivity is 97.2% and 99.1% with a Q-Factor of 19.08 and 155.98 at 1.9656 THz and 3.3692 THz, respectively, when transverse electromagnetic mode (TEM) was selected. The perforated star-shaped was evaluated for IBV (Family of COVID-19) regarding frequency deviation, sensitivity, and figure of merit. Results show that at 1.9656 THz, the proposed design gives 30.8 GHz, 940.49 GHz/RIU, and 8.6, respectively, for 0.01 (EID/5 µL concentration) and 4.4 GHz, 2200 × 103 GHz/RIU, and 20,215.014, respectively at 1.9612 THz for 1000 (EID/5 µL concentration). Although the obtained results demonstrate the efficiency of the proposed THz metamaterial biosensor in coronavirus detection, it has also been extended for other types of viruses, including H5N1, H5N2, H9N2, H4N6, and FAdV, based on the slight variations in their refractive indices. Additionally, the influence of the design parameters is optimized in order to achieve better performance.

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Section: Effect Of Bio-med Samplesmentioning

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Design and optimization of highly sensitive multi-band terahertz metamaterial biosensor for coronaviruses detection

2023

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“…Another analysis is also done in ref [57] for the lung cancer detection with a multiple modes integrated biosensor, based on higher-order Fano metamaterials. These results have been improved in terms of sensitivity and Qfactor in our ongoing work, which its initial results have been published in [58].…”

Section: B Early Cancer Cells Detection With Fano Resonance and Eitli...mentioning

confidence: 92%

Terahertz Metastructures for Noninvasive Biomedical Sensing and Characterization in Future Health Care [Bioelectromagnetics]

Nourinovin

Navarro‐Cía

Rahman

et al. 2022

IEEE Antennas Propag. Mag.

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“…On the other hand, THz spectroscopy [5] can be used for less complex, inexpensive, and precise identification of biomarkers and malignancies. To increase the sensitivity, THz spectroscopy can also be used in conjunction with electromagnetic biosensors, such as THz metamaterials and metasurfaces [6]- [8].…”

Section: Introductionmentioning

confidence: 99%

Terahertz Characterization of Ordinary and Aggressive Types of Oral Squamous Cell Carcinoma as a Function of Cancer Stage and Treatment Efficiency

Nourinovin,

Rahman,

Philpott

et al. 2023

IEEE Trans. Instrum. Meas.

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Oral squamous cell carcinoma (OSCC) has asymptomatic characteristics that make it challenging to identify in the early stages and lead to metastatic effects. Terahertz (THz) spectroscopy and imaging are recognized as a novel technique for early cancer detection due to the non-ionizing nature and the significant THz wave absorption by water's hydrogen bonds and the higher hydration of tumours. Despite this potential, there is a lack of research on the THz characterisation of oral cancer with various essential biological conditions. THz characterisation based on frozen, freshly excised tissue restricts parametric studies on important components and diverse biological situations. Therefore, we cultivated the three-dimensional (3D), organotypic model of the OSCC, to investigate the THz spectroscopy of the tumour at various phases and the effects of the anticancer drug AG1478 on its THz spectra. Moreover, we have compared the characterisation of OSCC with two levels of aggressiveness and we contrasted how well the medication worked on these two types of cell lines. The measurements were performed at the frequency range of 0.4 to 1.6 THz, and with increasing malignancy of the samples, we observed higher refractive index, absorption coefficient, and complex permittivity than normal tissue. The results demonstrates that whereas AG1478 shifts the THz spectra in the direction of the normal tissue, it has no effect on aggressive OSCC (AOSCC) under the same circumstances. These findings may contribute to techniques that diagnose and detect tumours at the early stage.

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A Terahertz Electromagnetically Induced Transparency-Like Metamaterial for Biosensing

Cited by 9 publications

References 24 publications

Design and optimization of highly sensitive multi-band terahertz metamaterial biosensor for coronaviruses detection

Design and optimization of highly sensitive multi-band terahertz metamaterial biosensor for coronaviruses detection

Terahertz Metastructures for Noninvasive Biomedical Sensing and Characterization in Future Health Care [Bioelectromagnetics]

Terahertz Characterization of Ordinary and Aggressive Types of Oral Squamous Cell Carcinoma as a Function of Cancer Stage and Treatment Efficiency

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