Preliminary results of a systematic study on the simultaneous optical-to-X-rays variability in blazars are presented. Data from Swift observations of four bright γ−ray blazars (3C 279, ON +231, S5 0716+71, PKS 2155−304) have been analyzed, compared, and discussed. Specifically, 3C 279 shows a variable flattening in the low energy part of the X-ray spectrum that appears to be confined in a specific X-ray vs optical/UV fluxes region. Some implications are shortly analyzed.