A thoracic parasternal granular cell tumor in a child: About one case and review of the literature, discussion about treatment guidelines, is complete resection compulsory?

Jaloux, Charlotte; Degardin, N.; Cegarra-Escolano, Marianne; Habib, M; Philandrianos, C.; Casanova, Dominique

doi:10.1016/j.anplas.2016.12.004

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“…A wide excisional margin is optimal because of the infiltrative pattern of growth and the tendency to recur. It has been described that MGCTs can result from malignant transformation of benign GCT, so margins preservation is highly recommended also for benign--appearing lesions [6][7][8].…”

Section: Discussionmentioning

confidence: 99%

Malignant granular cell tumor of the lumbar region – a case report and review of the criteria for diagnosis

Stanowska¹,

Morysiński

Rutkowski

et al. 2020

Nowotwory. Journal of Oncology

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We report an unusual case of a malignant granular cell tumor of the left lumbar region in 63-year old woman-diagnosed, consulted and treated with surgical resection (R1) and radiotherapy, followed up for 2 years with lung metastases after 22 months. Furthermore, we discuss histopathological differential diagnosis and current criteria for malignancy, as well as available options for systemic treatment in view of cytogenetic and molecular genetic characteristics of the tumor.

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Section: Discussionmentioning

confidence: 99%