A thorough physicochemical characterisation of 14 calcium phosphate-based bone substitution materials in comparison to natural bone

Tadic, D.; Epple, Matthias

doi:10.1016/s0142-9612(03)00621-5

Cited by 494 publications

(361 citation statements)

References 22 publications

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“…Presence of pores and maintenance of the trabeculated crystalline structure of the bone are factors that are fundamental for achieving success in relation to cellular phenomena of deposition of osteoprogenitor cells on the graft, reabsorption of the graft and formation of new bone in its place (15,16) . Some authors have reported the same observations in relation to the microscopic structure, in commercial products subjected to thermal processes of deproteinization, such as BioOss or GenOx Inorg (10,11,17) , or to physicochemical processing not involving high temperatures, such as bovine TutoPlast, Tutobone or human TutoPlast (17) , and also in non-commercial products subjected to physicochemical processes of cleaning and purification such as OBM (10) or Kiel bone (17) .…”

Section: Discussionmentioning

confidence: 63%

“…The mean size of the pores was 316 µm (146.7 µm), ranging from 91.2 to 497.8 µm, and 333.5 µm (304.8 µm), ranging from 87.2 to 963.9 µm, with 50x and 150x magnification, respectively (Table 2) (17,18) .…”

Section: Discussionmentioning

confidence: 99%

“…X-ray diffraction analysis was used to determine the chemical composition of OrthoGen, and this was indicative of the presence of different phases in the sample, with regard to the purity of the material and the percentage crystallinity (17,19,20) . There are several systems that make it possible to determine the peak produced by a given element and to locate it in the test sample, thus producing a map of its distribution.…”

Section: Discussionmentioning

confidence: 99%

“…In the study conducted by Tadic and Epple (17) , several types of bone substitutes of synthetic or natural origin were characterized. With regard to determining the mineral phase, the characteristic peak of hydroxyapatite that is located around 32°2θ was detected in all the samples studied.…”

Section: Discussionmentioning

confidence: 99%

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Caracterização físico-química do enxerto de osso bovino liofilizado

Gália¹,

Lourenço²,

Rosito³

et al. 2011

Rev. bras. ortop.

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Objective: To evaluate the physicochemical characteristics of lyophilized bovine grafts manufactured on a semi-industrial scale (Orthogen; Baumer S/A*) in accordance with a protocol previously developed by the authors. Methods: The lyophilized bovine bone grafts were characterized by means of scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffractometry (XRD), thermogravimetric (TG) analysis, differential exploratory scanning calorimetry (DSC) and Fourier-transform infrared (FT-IR) spectroscopy. Results: Ca was the main component (60%) found in the samples, followed by P (28%) and O (5%). The mean (sd) pore size was 316 µm (146.7), ranging from 91.2 to 497.8 µm, andRev Bras Ortop. 2011;46(4):444-51

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Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Caracterização físico-química do enxerto de osso bovino liofilizado

Gália¹,

Lourenço²,

Rosito³

et al. 2011

Rev. bras. ortop.

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“…Although autogeneous bone continues to be the "gold standard" in bone substitution [13][14][15][16][17][18][19][20], its limited availability and the need for a second surgical site and procedure drove the quest to other alternatives, like allografts (from cadavers), xenografts (from animals) and numerous synthetic materials [15-17, 20, 21], all having merits and limitations [13,15].…”

Section: Introductionmentioning

confidence: 99%

Comparison of a xenogeneic and an alloplastic material used in dental implants in terms of physico-chemical characteristics and in vivo inflammatory response

Figueiredo

Coimbra

Cabrita

et al. 2013

Materials Science and Engineering: C

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Two commercial bone grafts used in dentistry (Osteobiol Gen-Os®, a xenograft of porcine origin, and Bonelike®, a hydroxyapatite based synthetic material), in the form of granules, were characterized and evaluated in vivo regarding the intensity of the tissue inflammatory response. These biomaterials were characterized in terms of morphology, particle size distribution, porosity and pore size, specific surface are and density. The chemical composition and structure of the materials were accessed by Fourier-Transform Infrared Spectroscopy (FTIR) and X-ray Diffraction (XRD). The graft materials were implanted in the gluteus maximus muscles of Wistar rats and the inflammatory response evaluated through histological analysis, after one week of implantation.The results showed that the two grafts have quite different characteristics in practically all the evaluated properties. While Osteobiol® exhibits a structure and composition similar to the natural bone, Bonelike® is constituted by a main crystalline phase of hydroxyapatite and two secondary phases of -and -tricalcium phosphate. Osteobiol® granules, besides being larger, are irregular, and exhibit sharp-edged tips, while those of Bonelike® are approximately cylindrical, with round contours, and more uniform in size. The in vivo response evaluated from the inflammatory infiltrates revealed that although both implants did not cause severe inflammation, Bonelike® granules elicit a consistently more intense inflammatory reaction than that triggered by the granules of Osteobiol®, particularly in terms of collagen production and formation of fibrous capsule. This reaction was partly explained in terms of the characteristics evaluated for the granules of this material.

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Metal Matrix Composites: Magnesium

Luthringer¹,

Hort²,

Feyerabend³

2011

Wiley Encyclopedia of Composites

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In this article, special attention is drawn to magnesium‐based metal matrix composites (MMCs). The first part reviews the conventional and the newer processing techniques appropriate for the fabrication of magnesium matrix composites. These routes are divided into liquid‐ and solid‐state fabrication, in situ , and spray forming methods. After introducing the matrix and its properties, reinforcements are described (continuous and discontinuous) and the obtained composites are discussed. The interface is also described. Finally, recent applications, such as medical purpose, are reported.

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A thorough physicochemical characterisation of 14 calcium phosphate-based bone substitution materials in comparison to natural bone

Cited by 494 publications

References 22 publications

Caracterização físico-química do enxerto de osso bovino liofilizado

Caracterização físico-química do enxerto de osso bovino liofilizado

Comparison of a xenogeneic and an alloplastic material used in dental implants in terms of physico-chemical characteristics and in vivo inflammatory response

Metal Matrix Composites: Magnesium

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