A turn-on fluorescent probe based onN-(rhodamine-B)-thiolactam-2-n-butane with ionic liquids for selective and sensitive detection of mustard gas stimulant

Abstract

SRB-NB/ILs was able to detect 2-CEES in liquid and gaseous form with excellent selectivity and sensitivity. Thus, we envisage that the probe could be applied for rapid and reliable detection of SM in various emergency scenarios.

Fluorescent probes for the detection of chemical warfare agents

“…Li and co-workers explored a similar strategy using fluorescent probe SRB-NB (14), and an IL (1-butyl-3-methylimidazolium dicyandiamide). 52 In the presence of SM, the SRB-NB/IL system exhibited a significant fluorescence increase at 583 nm, and an LOD of 3 mM was determined. The Song group designed and synthesized a series of probes (15)(16)(17)(18)(19)(20) for the selective detection of SM.…”

“…To date, the available fluorescent probes for the detection of blister agents are rather limited: 9 references for SM and 1 for Lewisite. [44][45][46][47][48][49][50][51][52][53][54][55] No report exists on a fluorescent probe that can detect either phosgene oxime or nitrogen mustard. Since blister agents are toxic and are controlled substances, researchers use less-toxic blister agent mimics such as 2-chloroethyl ethyl sulfide (CEES) to evaluate the fluorescent probe.…”

An AIE fluorescent sensor for rapid and selective detection of phosgene

“…2 During World War I, phosgene was introduced as a chemical warfare agent (CWA) and caused more than 80% of the CWA-related fatalities. 3 Unlike other strictly regulated and prohibited CWAs 4 (such as sarin, soman, VX and mustard gas), phosgene is an important material that has been widely used in the agriculture industry, pharmaceutical industry, textile industry and so on. 5 Therefore, it carries enormous risks to public health and environmental security if unexpected industrial accidents or intentional nefarious releases occur.…”

Ultrafast Sulfur Mustard Simulant Gas Fluorescent Chemosensors Based on Triazole AIEE Material with High Selectivity and Sensitivity at Room Temperature

“…To achieve this aim, currently, one method is to improve the electrophilic ability of SM by utilizing ionic liquids or polar solvents. 30 In such a way, SM spontaneously undergoes intramolecular cyclization to form a hyperactive three-membered cationic sulfonium heterocycle intermediate, and the sulfur cation intermediate with stronger electrophilic ability reacts readily with nucleophile sensing materials. 31 However, this way also seriously limits the gas-phase detection of fluorescent chemosensors in the real field.…”

“…Based on this point, the electrophilic ability of SM and the nucleophilic ability of the chemosensor are the keys to achieve effective fluorescence sensing performances. To achieve this aim, currently, one method is to improve the electrophilic ability of SM by utilizing ionic liquids or polar solvents . In such a way, SM spontaneously undergoes intramolecular cyclization to form a hyperactive three-membered cationic sulfonium heterocycle intermediate, and the sulfur cation intermediate with stronger electrophilic ability reacts readily with nucleophile sensing materials .…”