A unified theory of retention and selectivity in liquid chromatography. 1. Liquid-solid (adsorption) chromatography

Chromatography—A Unified Science

“…This definition broadens earlier concepts [1][2][3][4][5][6][7], but recognizes and builds on our history, opens the door to a practice of chromatography quite different from what we have done so far, and provides at least a glimpse at where we might be headed in the future. Our challenge in further developing chromatography is to abandon any perceived but unreal restrictions on what we can do, and then expand the scope of separations while keeping balance between practical utility and actual needs in the workplace.…”

Liquid‐solid chromatography. Recent progress in theoretical studies concerning the dependence of the capacity ratio upon the mobile phase composition

“…In our opinion, they provide a simple and immediately clear theoretical explanation of the relationships utilized in LSC with mixed mobile phases. As regards further theoretical studies on the LSC process with mixed mobile phases, its detailed description on the basis of statistical thermodynamics would be useful; studies in this direction have been undertaken by Jaroniec et al [21] and recently by Martire and Boehrn [81,82].…”

Selectivity in normal-phase liquid chromatography with binary mobile phase

“…Numerous models have been developed to describe the retention in liquid solid chromatography with mixed mobile phases, several reviews cover the results (Borówko 2002;Jaroniec 1983a, 1983b;Jaroniec et al 1985;Nurok 1989;Snyder 1969;Soczewiński 2002). These approaches involve various factors, namely, interactions with the surface Jandera et al 2001;Jaroniec et al 1978;Scott and Kucera 1975;Snyder and Glajch 1981), non-specific interactions in the liquid phase (Boehm and Martire 1980;Borówko 1984) association and solvation effects Jaroniec 1983a, 1983b;Jaroniec et al 1985) differences in molecular sizes of components (Borówko 1986)), energetical heterogeneity of the adsorbent (Borówko 2002;Borówko and Jaroniec 1979;Jaroniec and Ościk-Mendyk 1981), orientation of solute molecules on the surface (Borówko 1988), etc. Nevertheless, theoretical aspects of liquid adsorption chromatography still remain a matter of the debate in the literature.…”