A useful macrocyclic combination of pillar[5]arene and Bodipy for fluorometric analysis of Hg2+: High-resolution monitoring in fish sample and living cells

Yemisci, Elif; Kurşunlu, Ahmed Nuri; Oğuz, Mehmet; Oguz, Alev

doi:10.1016/j.molliq.2022.120940

Cited by 13 publications

(1 citation statement)

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“…Optical techniques such as absorption spectroscopy and spectrofluorimetry rely on changes in color or fluorescence intensity and are not hindered by these problems [ 14 , 15 ]. Fluorescent chemosensors for Hg 2+ ions are mainly derived from carbon dots [ 16 , 17 ], metal–organic frameworks [ 18 , 19 ], porphyrin [ 20 ], BODIPY [ 21 , 22 ], naphthalimide [ 23 ], coumarin [ 24 ], rhodamine [ 25 , 26 ], and fluorescein [ 27 , 28 , 29 ]. The development of new chemosensors for mercury ions is an important goal for researchers worldwide due to adverse environmental conditions.…”

Section: Introductionmentioning

confidence: 99%

Shedding Light on Heavy Metal Contamination: Fluorescein-Based Chemosensor for Selective Detection of Hg2+ in Water

Zavalishin,

Kiselev,

Isagulieva

et al. 2024

IJMS

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This article discusses the design and analysis of a new chemical chemosensor for detecting mercury(II) ions. The chemosensor is a hydrazone made from 4-methylthiazole-5-carbaldehyde and fluorescein hydrazide. The structure of the chemosensor was confirmed using various methods, including nuclear magnetic resonance spectroscopy, infrared spectroscopy with Fourier transformation, mass spectroscopy, and quantum chemical calculations. The sensor’s ability in the highly selective and sensitive discovery of Hg2+ ions in water was demonstrated. The detection limit for mercury(II) ions was determined to be 0.23 µM. The new chemosensor was also used to detect Hg2+ ions in real samples and living cells using fluorescence spectroscopy. Chemosensor 1 and its complex with Hg2+ demonstrate a significant tendency to enter and accumulate in cells even at very low concentrations.

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