Relevance. Virtual organizations and virtual teams are considered a response to the tightening requirements of modern business – deadlines, quality, efficiency, especially in a global environment. The pandemic has accelerated the tendency to expand the use of these structures in the country's economy as a whole, as well as at the regional level. Cooperation within the framework of the VO contributes to flexibility, efficiency, customer orientation and risk reduction. In order for virtual organizations to fully use their advantages, it is necessary to take into account that due to the specifics of such organizations in the field of PPP in the regional economy, certain additional problems may arise when managing them that are not typical for traditional organizations.The purpose of the study is to generalize, systematize and verify the problems of managing virtual organizations in the regional economy.Objectives: to substantiate the relevance of identifying and taking into account the problems of managing virtual organizations in the field of public-private partnership; to systematize the problems of managing virtual organizations noted in scientific publications; to verify the information obtained using interviews with Russian managers directly related to virtual organizations and implementing projects in the field of PPP.Methodology. During the research, the method of desk research, semi-structured interviews, as well as the method of systematization, descriptive method were used.Results: the main problems of managing virtual organizations in general and at the regional level in particular are systematized.Conclusions. Many of the problems noted for virtual organizations and teams have a common nature with "traditional" management problems, but they become more relevant due to the specific features of the organization of work. In general, the problems identified by the respondents correlate with the problems of managing virtual organizations noted in scientific publications. Taking into account the possibilities of such problems in practice and proactive management will enable virtual organizations to fully use the advantages in the field of PPP in the regional economy.
