A wearable, cotton thread/paper-based microfluidic device coupled with smartphone for sweat glucose sensing

Xiao, Gang; He, Jing; Chen, Xiaodie; Qiao, Yan; Wang, Feng; Xia, Qingyou; Yu, Ling

doi:10.1007/s10570-019-02396-y

Cited by 132 publications

(89 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

Section: Resultsmentioning

confidence: 99%

“…These types of applications are extremely different in terms of the variety of chemical structures to be analyzed (samples) and the functionality of the smartphone application used to process the samples. [161][162][163][164][165][166][167] Imaging techniques are not popular in this category, as the adapter consists of special electronics that are designed specifically to target a unique chemical compound. [168][169][170][171][172][173][174] Using a smartphone proved to be cost effective (see Figure 12), and extremely accurate results were reported when comparing the performance of the smartphone-based adapters to those of laboratory equipment and devices with a low CV%, a high regression coefficient, lower costs, and a low LOD (see Figures 10 to 13).…”

Section: Electrochemical Applicationsmentioning

confidence: 99%

See 1 more Smart Citation

A review of smartphone point‐of‐care adapter design

Alawsi

Al-Bawi

2019

Engineering Reports

View full text Add to dashboard Cite

In this review, we explore the potential of smartphone‐based applications based on their unique ability to support portable, easy‐to‐use, precise, and efficient functions, which, in turn, makes lab‐on‐hardware a trending area of novel research. Smartphones can assist surgeons, physicians, biologists, chemists, ophthalmologists, and laboratory technicians in maintaining an easy‐to‐use, cost‐effective, and integrated environment for treatment, diagnosis, and point‐of‐care (POC) applications. These POC applications can improve patients' quality of life, offering patients a precise diagnosis and the correct treatment. This is a noble goal that aims to reduce costs and to increase the accuracy of sample testing, treatment, and diagnosis. Recent innovations have made major advances in smartphone adapters, providing portability, robustness, self‐powered devices, small‐sized adapters, and ease of usage. Lab‐on‐hardware is a progressing field, and smartphone imaging applications are increasingly expanding, resulting in POC applications with the latest and most advanced image analysis, enhancement, recognition, and other image processing techniques. The most recent studies in the field are explored to provide a solid background to interested researchers against which they can choose of application and/or adapter design they aim to develop, with a discussion of the methods reviewed here.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Electrochemical Applicationsmentioning

confidence: 99%

A review of smartphone point‐of‐care adapter design

Alawsi

Al-Bawi

2019

Engineering Reports

View full text Add to dashboard Cite

show abstract

“…The fabric was originally laid horizontally to test the droplet behavior against the gravity and then was rotated into different angles to check the transport and roll-off behaviors. The artificial sweat was prepared according to ISO 3160-2, which comprises NaCl (20 g/liter), NH 4 Cl (17.5 g/liter), acetic acid (5 g/liter), and d,l-lactic acid (15 g/liter), with the pH adjusted to 4.7 by NaOH (37,38).…”

Section: Water Shower Testmentioning

confidence: 99%

“Skin-like” fabric for personal moisture management

et al. 2020

View full text Add to dashboard Cite

Personal moisture management fabrics that facilitate sweat transport away from the skin are highly desirable for wearer’s comfort and performance. Here, we demonstrate a “skin-like” directional liquid transport fabric, which enables continuous one-way liquid flow through spatially distributed channels acting like “sweating glands” yet repels external liquid contaminants. The water transmission rate can be 15 times greater than that of best commercial breathable fabrics. This exceptional property is achieved by creating gradient wettability channels across a predominantly superhydrophobic substrate. The flow directionality is explained by the Gibbs pinning criterion. The permeability, mechanical property, and abrasion resistance (up to 10,000 cycles) of the fabric were not affected by the treatment. In addition to functional clothing, this concept can be extended for developing materials for oil-water separation, wound dressing, geotechnical engineering, flexible microfluidics, and fuel cell membranes.

show abstract

“…LOC can be fabricated on different materials such as glass , silicon , PDMS , PMMA [, paper or a hybrid of PDMS/paper/glass . Presently, thread/PADs can also be fabricated as a simple platform for bioassays . In addition, a commonly used toner (a powder consisting of polymer [acrylate and styrene] and iron oxide or silicon dioxide ) in laser printers or photocopiers can be utilized as a novel and cost‐effective platform for LOC devices.…”

Section: Brief History Of Paper‐based Analytical Devicesmentioning

confidence: 99%

“…The wearable device was successfully applied to monitor the glucose concentration in saliva after the ingestion of chocolate. Xiao and co‐workers fabricated a wearable, cotton thread/paper‐based microfluidic device coupled with a smartphone for sweat glucose sensing . The hydrophilic cotton thread was plasma‐treated and used as a microchannel to harvest sweat and guided the sweat to a paper‐based colorimetric detection.…”

Section: Future Outlookmentioning

confidence: 99%

Recent applications of paper‐based point‐of‐care devices for biomarker detection

Suntornsuk

2019

Electrophoresis

View full text Add to dashboard Cite

Detection of biomarkers is essential for diagnosis and prognosis of diseases for healthcare teams to provide timely appropriate treatments. Reliable, inexpensive, and sensitive devices are desirable to serve this purpose. Paper‐based analytical devices (PADs) have gained enormous attention during the past decade as point‐of‐care devices for biomarker detection due to their simplicity, portability, and biocompatibility. Importantly, the devices highly comply with the WHO “ASSURED” concept (i.e. Affordable, Sensitive, Specific, User‐friendly, Rapid and Robust, Equipment free, and Deliverable to end‐users). Thus, PADs could be sustainably alternative tools for biomarker detection, especially in resources‐constraint areas where budget, skillful operators, and health infrastructure are limited. First, this review introduces overviews of biomarkers, their detection and brief history of PADs. Second, description of common fabrication and detection techniques in PADs are provided. Then, it highlights recent state of the art technologies and applications of PADs for various biomarker detection published during 2018 to May 2019. Applications for tumor marker, cardiac and coronary heath disease, and metabolic disorder biomarker detection are tabulated and selected examples are described in details. Finally, it discusses the current challenges, advances, and novel applications of PADs. The review would be valuable for healthcare workers using PADs as cost‐effective point‐of‐care devices for biomarker detection and for researchers working on future developments of the devices.

show abstract

A wearable, cotton thread/paper-based microfluidic device coupled with smartphone for sweat glucose sensing

Cited by 132 publications

References 24 publications

A review of smartphone point‐of‐care adapter design

A review of smartphone point‐of‐care adapter design

“Skin-like” fabric for personal moisture management

Recent applications of paper‐based point‐of‐care devices for biomarker detection

Contact Info

Product

Resources

About