A Welsh-sparing dysphasia

Rice, Sam; Boregowda, Kusuma; Williams, Meurig T; Morris, GC; Okosieme, Onyebuchi

doi:10.1016/s0140-6736(13)61837-1

Cited by 12 publications

(8 citation statements)

References 4 publications

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“…Despite advanced laboratory techniques and increased awareness of the disease, there are still cases of excessive dysfunction. (14,15). Hypo -and hyperthyroidism are usually caused by pathological processes in the thyroid gland, but may be caused by hypothalamus or pituitary (central hypothyroidism) or functional thyroid disorders in certain situations (16).…”

Section: Discussionmentioning

confidence: 99%

The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status

Kar

Kiraz

Kocatürk

et al. 2020

Clinical and Experimental Health Sciences

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Objective: We aimed to investigate neutrophil lymphocyte ratio (NLR), leukocyte count (WBC), mean platelet volume (MPV) and C-reactive protein levels (CRP) as inflammatory markers according to thyroid function status in hypo-hyperthyroidism patients.Methods: Data of patients (n=454, age>18) who applied to the Eskisehir Osmangazi University Hospital between March 2018 and December 2018 were evaluated retrospectively. There were 79 patients in hyperthyroidism group (TSH<0.27 µIU/ml, group I), 297 patients in euthyroid group (TSH=0.27-4.2 µIU/ml, group II) and 78 patients in hypothyroidism group (TSH>4.2 µIU/ml, group III).Results: Serum TSH, fT4, fT3, anti-TG and anti-TPO levels were found statistically different between groups (p<0.001) but there were no significant difference in WBC, NLR and MPV between groups. There was a positive correlation between the NLR and CRP (r=0,295, p<0.01). In addition, NLR was positively correlated with WBC (r=0,412, p<0.001). Serum CRP levels were statistically higher in group I (3.5 mg/L [1.50-11]) than group II (2.1 mg/L [0.86-5.42]), (p<0.001). Although CRP levels were higher in group III (2.5 mg/L [1.18-5.73]) than group II, there was no significant difference. CRP showed weak positive correlation with fT4 (r=0,118, p<0.05) and negative correlation with TSH (r=-0,108, p<0.05). Conclusion:High CRP levels may play an important role in the evaluation of hyperthyroidism in terms of thyroid dysfunction observed in the present study.

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Section: Discussionmentioning

confidence: 99%

The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status

Kar

Kiraz

Kocatürk

et al. 2020

Clinical and Experimental Health Sciences

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“…4,35 Indeed, the literature is rife with reports of atypical cases with a plethora of neurologic and psychiatric manifestations. 4,36,37 The extreme state of myxoedema coma is less common nowadays but is still encountered in the elderly with neglected disease. 38 The diagnosis of primary hypothyroidism should always be confirmed by the finding of an elevated serum thyroid stimulating hormone (TSH) concentration.…”

Section: Diagnosismentioning

confidence: 99%

Thyroxine replacement: a clinical endocrinologist’s viewpoint

et al. 2016

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“…Thyroid dysfunction is common, readily identifiable and easily treatable but if undiagnosed or untreated can have profound adverse consequences 2,3 . Despite an increase in thyroid disease awareness and the availability of sensitive laboratory assays for the measurement of thyroid hormones it is remarkable that instances of extreme thyroid dysfunction continue to occur 4,5 . Hypothyroidism and hyperthyroidism most commonly arise from pathology within the thyroid gland (primary thyroid disease), although rarely they may arise from disorders of the hypothalamus or pituitary (central) or from peripheral causes 6 .…”

Section: Introductionmentioning

confidence: 99%

Global epidemiology of hyperthyroidism and hypothyroidism

et al. 2018

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Thyroid hormones are essential for growth, neuronal development, reproduction and regulation of energy metabolism. Hypothyroidism and hyperthyroidism are common conditions with potentially devastating health consequences that affect all populations worldwide. Iodine nutrition is a key determinant of thyroid disease risk; however, other factors, such as ageing, smoking status, genetic susceptibility, ethnicity, endocrine disruptors and the advent of novel therapeutics, including immune checkpoint inhibitors, also influence thyroid disease epidemiology. In the developed world, the prevalence of undiagnosed thyroid disease is likely falling owing to widespread thyroid function testing and relatively low thresholds for treatment initiation. However, continued vigilance against iodine deficiency remains essential in developed countries, particularly in Europe. In this report, we review the global incidence and prevalence of hyperthyroidism and hypothyroidism, highlighting geographical differences and the effect of environmental factors, such as iodine supplementation, on these data. We also highlight the pressing need for detailed epidemiological surveys of thyroid dysfunction and iodine status in developing countries.

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A Welsh-sparing dysphasia

Cited by 12 publications

References 4 publications

The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status

The Level of Serum C-Reactive Protein and Neutrophil Lymphocyte Ratio According to Thyroid Function Status

Thyroxine replacement: a clinical endocrinologist’s viewpoint

Global epidemiology of hyperthyroidism and hypothyroidism

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