A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles
Hilda Amekyeh,
Rayan Sabra,
Nashiru Billa
Abstract:Oral administration of dosage forms is convenient and beneficial in several respects. Lipid nanoparticulate dosage forms have emerged as a useful carrier system in deploying low solubility drugs systemically, particularly class II, III, and IV drugs of the Biopharmaceutics Classification System. Like other nanoparticulate delivery systems, their low size-to-volume ratio facilitates uptake by phagocytosis. Lipid nanoparticles also provide scope for high drug loading and extended-release capability, ensuring dim… Show more
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