A wireless paired emitter detector diode device as an optical sensor for Lab-on-a-disc applications

Gorkin, Robert; Czugala, Monika; Rovira-Borras, Carlos; Ducrée, Jens; Diamond, Dermot; Benito‐Lopez, Fernando

doi:10.1109/transducers.2011.5969761

Cited by 5 publications

(6 citation statements)

References 18 publications

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“…Previously, it has been applied for quantifying the BCP dye. 17 The spectrophotometric data confirmed the results of our proposed sensor.…”

Section: Real Sample Studysupporting

confidence: 80%

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Red gum-capped gold nanoparticles for electrochemical sensing of bromocresol purple in water

Zahran,

Azzem,

El-Attar

2024

Mater. Adv.

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“…Previously, it has been applied for quantifying the BCP dye. 17 The spectrophotometric data confirmed the results of our proposed sensor.…”

Section: Real Sample Studysupporting

confidence: 80%

“…Previously, the BCP dye was optically detected with an LOD of 135 ppm, confirming the high sensitivity of our proposed electrochemical sensor. 17 Moreover, it exhibited a high sensitivity with a value of 0.14 μA mg −1 L −1 cm −2 (Table 1). Additionally, the sensor showed accepted repeatability with an RSD value of 1.98%.…”

Section: Resultsmentioning

confidence: 99%

Red gum-capped gold nanoparticles for electrochemical sensing of bromocresol purple in water

Zahran,

Azzem,

El-Attar

2024

Mater. Adv.

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“…4 Calibration curves of BCP pH dye in solution, n = 6, using a UV-Vis spectrometer (top) and the PEDD system (bottom), L UV-Vis = 1 cm, L PEDD = 0.16 cm. 52 Further, a remarkable improvement in long-term sensor stability was achieved by ensuring covalent immobilisation of the ionogel to the surface of the PMMA substrate. This avoided the delamination of the swollen ionogel from the microfluidic device during sample analysis over time.…”

Section: Ionogel Optical Calibration Using the Lab-on-a-disc With Ped...mentioning

confidence: 99%

Optical sensing system based on wireless paired emitter detector diode device and ionogels for lab-on-a-disc water quality analysis

et al. 2012

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This work describes the first use of a wireless paired emitter detector diode device (PEDD) as an optical sensor for water quality monitoring in a lab-on-a-disc device.The microfluidic platform, based on an ionogel sensing area combined with a lowcost optical sensor is applied for pH (quantitative) and qualitative turbidity monitoring of water samples at the point-of-need. The autonomous capabilities of the PEDD system, combined with the portability and wireless communication of the full device, provide the flexibility needed for on-site water testing. Water samples from local fresh and brackish sources were successfully analysed using the device, showing very good correlation with standard bench-top systems.

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“…However, various schemes are well known to integrate a detector unit for absorption measurements with the instrument. 28,30,[32][33][34][35] For absolute quantification of nitrate/nitrite concentrations in blood, we calibrated with a nitrate dilution series (0, 12.5, 25 and 50 mM) in buffer using the previously described assay structure for whole blood (Fig. 5).…”

Section: Automation Of Colorimetric Assaymentioning

confidence: 99%

Comprehensive integration of homogeneous bioassays via centrifugo-pneumatic cascading

et al. 2013

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This work for the first time presents the full integration and automation concept for a range of bioassays leveraged by cascading a centrifugo-pneumatic valving scheme to sequentially move several liquids through shared channel segments for multi-step sample preparation into the detection zone. This novel centrifugo-pneumatic liquid handling significantly simplifies system manufacture by obviating the need for complex surface functionalization procedures or hybrid material integration, as it is common in conventional valving methods such as capillary burst valves or sacrificial valves. Based on the centrifugo-pneumatic valving scheme, this work presents a toolkit of operational elements implementing liquid loading/transfer, metering, mixing and sedimentation in a microstructured polymer disc. As a proof of concept for the broad class of homogeneous bioassays, the full integration and automation of a colorimetric nitrate/nitrite test for the detection of clinically relevant nitric oxide (NO) in whole blood is implemented. First, 40 μL of plasma is extracted from a 100 μL sample of human blood, incubated for one hour with the enzymatic mixture (60 μL), and finally reacted with 100 μL of colorimetric (Greiss) reagents. Following just a single loading phase at the beginning of the process, all of these steps are automated through the centrifugo-pneumatic cascade with a high level of flow control and synchronization. Our system shows good correlation with controls up to 50 μM of nitrate, which adequately covers the healthy human range (4 to 45.3 μM).

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A wireless paired emitter detector diode device as an optical sensor for Lab-on-a-disc applications

Cited by 5 publications

References 18 publications

Red gum-capped gold nanoparticles for electrochemical sensing of bromocresol purple in water

Red gum-capped gold nanoparticles for electrochemical sensing of bromocresol purple in water

Optical sensing system based on wireless paired emitter detector diode device and ionogels for lab-on-a-disc water quality analysis

Comprehensive integration of homogeneous bioassays via centrifugo-pneumatic cascading

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