A wireless remote high-power laser device for optogenetic experiments

Abstract

Optogenetics affords the ability to stimulate genetically targeted neurons in a relatively innocuous manner. Reliable and targetable tools have enabled versatile new classes of investigation in the study of neural systems. However, current hardware systems are generally limited to acute measurements or require external tethering of the system to the light source.Here we provide a low-cost, high-power, remotely controlled blue laser diode (LD) stimulator for the application of optogenetics in neuroscience, focusing on wearable and intelligent devices, which can be carried by monkeys, rats and any other animals under study. Compared with the conventional light emitting diode (LED) device, this LD stimulator has higher efficiency, output power, and stability. Our system is fully wirelessly controlled and suitable for experiments with a large number of animals.

A Survey of Recent Patents in Engineering Technology for the Screening, Separation and Processing of Eggshell

“…ES is an attractive and creative material for carving to produce artwork and decorative items. Thus, many tools including carving pens, sanders, fixing and attaching material have been patented for ES carving ( Shang, 2015 ; Wang and Cui, 2015 ; Gao and Xiao, 2016 ; Jiang, 2017 ; Chao et al, 2018 ; Zhu et al, 2018 ; Dai, 2019 ; Wang and Zhang, 2019 ; Wang et al, 2019 ; Zhang et al, 2019a ; Zou,2019a,b,c,d,e ).…”

“…The egg is held in position using a vacuum-actuated suction cup and engraved using a laser beam. The held egg is rotated and can be moved up and down to maximize the carving precision and through-put ( Wang and Cui, 2015 ). Similarly, a patent discloses a device for avian ES carving that is equipped with a sandblasting seal box, sand spray gun, conveyer belt, egg holder, iron hollow pattern model, and a programmable logic controller.…”

Regulating the Single-Mode Lasing Intensity of Semiconductor Lasers Without Wavelength Shift

“…Typically, changing the current injection is an effective way to regulate the lasing intensity, because the injection current can be easily manipulated by external power sources [6]. However, the injection current method has many inevitable disadvantages, such as the heat effect of current, which leads to red shift or blue shift in the lasing spectrum [7].…”