AB0 Blood Group and Deep Vein Thrombosis in Elderly and Senile Patients

Томченко, А.И.; Chechulova, A.V.; Нохрин, С. П.; Сорока, В. В.; Khomchuk, I.A.

doi:10.17116/flebo20211501133

Cited by 1 publication

(1 citation statement)

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“…Conversely, patients who moved little during the first 3 days after starting cancer treatment, or after surgery, had a higher incidence of thrombosis than active patients. The problem of thrombosis of the lower extremities in cancer patients is complex, and the pathogenesis occurs according to the mechanism of a "vicious circle" [8,9]. It is impossible to establish which factor will act first -it is impossible after the almost simultaneous action of a large amount of chemical and biological substances on the blood coagulation function of people with cancer.…”

Section: Introductionmentioning

confidence: 99%

Histological Changes in Muscles During the Lower Extremities Thrombosis in Individuals with Gastrointestinal Tract Cancer

Bodnar¹,

Bodnar²,

Bodnar³

et al. 2021

Int j pharm res allied sci

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Thrombosis is a common complication in cancer patients. In all cancer patients, changes occur that lead to arterial and venous thrombosis. It is not known for certain what exactly provokes the appearance of blood clots and causes disseminated intravascular coagulation (DIC). A morpho-histological study of the muscles of the lower extremities was carried out in two groups of people who suffered from cancer and had deep vein thrombosis of the lower extremities with subsequent migration of blood clots. In two groups of people who died due to the migration of blood clots from the veins of the lower extremities in the pulmonary artery, clear dystrophic changes in muscle fibers were found with narrowing of all arterioles and a strong expansion of the venous vessels. In all the venous vessels of the preparation, damage to the endothelium was found, which may indicate the presence of thrombosis of the venous vessels carrying blood from the muscles. People with cancer of the pancreas and/or colon have significant hemodynamic, hypertrophic, dystrophic, and atrophic changes in muscle fibers. There are signs of a systemic effect of the tumor on the vessels and hemodynamics in the lower extremities.

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Section: Introductionmentioning

confidence: 99%