AB0 Blood Group Phenotypes and Rhesus Factor in The Pathogenesis of Gestational Diabetes Mellitus

Abstract

Objective: Some AB0 blood group phenotypes may be considered as risk factors in the pathogenesis of both type II diabetes mellitus (DM) and type I DM. The aim of this research was to investigate whether there is a relation between AB0 blood group phenotypes and Rhesus (Rh) factor and the occurrence of the disease in pregnant female diagnosed with gestational diabetes mellitus (GDM). Method: This research was case-control research, and the data were analyzed retrospectively. Pregnant women who were admitted to a research and teaching hospital for one year and underwent a 75 gram oral glucose tolerance test (OGTT) were included in the research. Pregnant females diagnosed with GDM according to OGTT results were separated into two groups as case group and healthy pregnant females as control group. Result: The prevalence of GDM was found to be 15.94% in a one-year data review. The mean age of pregnant females with GDM was higher than healthy pregnant females (p0.05). Rh factor positivity of both groups was not different (p>0.05). Conclusion: In conclusion, no association was found between the pathogenesis of GDM and AB0 blood group phenotypes and Rh factor.