Abdominal aortic aneurysm associated with aortic hypoplasia and polycystic kidneys

Abstract

The Editors invite readers to submit letters commenting on the contents of articles that appear in the Journal. Also welcome are brief communications in letter form reporting investigative or clinical observations without extensive documentation and with brief bibliography (five titles or less), not requiring peer review but open to critique by readers. Letters to the Editors should be no more than 500 words in length and they may have to be edited for publication.Abdominal aortic aneurysm associated with aortic hypoplasia and polycystic kidneys

Surgical management of abdominal aortic aneurysm associated with polycystic kidney disease: Report of two cases

“…Patients with PKD usually are complicated by hypertension and renal dysfunction, and these complications may lead to the formation of AAA. 2,3,6,14 Recently, an outstanding hypothesis was proposed This report AA, aortic aneurysm; NS, not stated regarding the fact that matrix metalloproteinases synthesized and secreted by kidney tubules of PKD play a critical role in the development of a concurrent AAA, 15 and this biomolecular investigation thus indicated the existence of a close relationship between AAA and PKD.…”

“…[1][2][3][4][5][6][7][8][9] The frequency of AAA in the patients with PKD ranged from approximately 5% to 10%. 1,3,13 Controversy still exists regarding the relationship between AAA and PKD.…”

“…[1][2][3][4][5][6][7][8][9] In surgically treating patients suffering from both AAA and PKD, it is often diffi cult to expose the aneurysm because of huge kidneys. We herein report two patients with concomitant AAA and PKD, who both underwent a safe and successful aneurysmectomy reconstructed with a bifurcated prosthetic graft after obtaining an adequate operative fi eld by a left nephrectomy.…”

Hypoplasia and fibromuscular dysplasia of infrarenal abdominal aorta with downstream aneurysm: Case report and review of the literature

“…The coassociation of AH with infrarenal aortic aneurysm has been described exceptionally 17 and in patients older than those with AH only. This suggests that agerelated degenerative processes or poststenotic hemodynamic mechanisms are involved.…”

A tale of an unfortunate outcome in COVID-era

“…[6][7][8][9] Though some studies did not find any association between ADPKD and aortic aneurysm, 10 others find that there was increased incidence of aortic aneurysm in patients with ADPKD ranging from 5-9.7% of patients. [11][12][13][14][15] The pathogenesis is still not clear; why some ADPKD patients developed aortic aneurysm and other do not. Whether the renal disease itself causes aortic aneurysm or is associated with the fact that many of these patients have hypertension, atherosclerosis and may are undergoing renal replacement therapy.…”