Ability to biofilm formation in infectious agents isolated from patients of a large general children’s hospital

Abstract

Objective: The study objective is to analyze biofilm formation in microorganisms isolated from patients of children’s hospital with severe purulent septic diseases.Methods: The ability to biofilm formation was studied in microorganisms isolated from 32 patients aged from 1 to 15 y.o. with sepsis, acute hematogenous osteomyelitis, peritonitis, and pneumonia in intensive care unit of regional general children’s hospital. Blood, phlegm, bronchial and oropharyngeal washings, wound fluid, peritoneal fluid served as specimens.Results: All tested strains have the ability to biofilm formation; moreover, the majority of them formed moderate biofilms.Conclusion: The common spread of biofilm infections can be related to the most important factors of preservation and distribution of microorganisms in health facilities which significantly limit preventive and therapeutic measures.

Identification of Infectious Diseases Patterns in the Combined Use of Bacteriological Diagnostics and MALDI Biotyper

“…Результаты отечественных исследований показали, что большинство госпитальных штаммов обладает способностью продуцировать биоплёнки. Это может способствовать их повышенной устойчивости и сопровождаться увеличением заболеваемости внутрибольничными инфекциями [4,5,6]. Основой эффективных лечебно-профилактических мероприятий является быстрая и качественная идентификация возбудителя.…”