2022
DOI: 10.21203/rs.3.rs-1767827/v1
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Abnormal Neural Differentiation in Response to Graphene Quantum Dots through Histone Modification Interference

Abstract: Background Graphene quantum dots (GQDs) have been broadly applied in biomedicine in recent years, and their environmental exposure and toxicological impacts have raised increasing concerns. The nanosafety assessment on the nervous system is one of the most important aspects, and potential effects of GQDs on neurodevelopment and the underlying mechanism are still elusive. In this study, the neural developmental toxicities of hydroxylated GQDs (OH-GQDs) and amino functionalized GQDs (NH2-GQDs) were investigated… Show more

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