Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study

Hashem, Mada; Shafqat, Qandeel; Wu, Ying; Rho, Jong M.; Dunn, Jeff F.

doi:10.1016/j.neuroimage.2022.118935

Cited by 11 publications

(18 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A number of different NIRS modalities were examined for their association with CBF. CW-NIRS was the most frequently utilized modality and was compared to CBF in 28 studies (Pryds et al, 1990(Pryds et al, , 2005Skov et al, 1991;Bucher et al, 1993;Kaminogo et al, 1995;Kirkpatrick et al, 1995;Hock et al, 1997;Holzschuh et al, 1997;Newton et al, 1997;Villringer et al, 1997;Goddard-Finegold et al, 1998;Pellicer et al, 1999;Yamaguchi et al, 1999;Soul et al, 2000;Ogasawara et al, 2003;Huppert et al, 2006;Murata et al, 2006;Ricci et al, 2006;Naulaers et al, 2007;Themelis et al, 2007;Kim et al, 2010;Taussky et al, 2012;Alderliesten et al, 2014Alderliesten et al, , 2017Wintermark et al, 2014;Alosh et al, 2016;Polinder-Bos et al, 2020;Hashem et al, 2022). DCE-NIRS was the next most commonly used modality with its relationship to CBF examined in 12 studies (Kuebler et al, 1998;Roberts et al, 1998;Brown et al, 2001Brown et al, , 2002De Visscher et al, 2003;Keller et al, 2003;Rothoerl et al, 2003;Schytz et al, 2009;Elliott et al, 2010Elliott et al, , 2014Saito ...…”

Section: Search Results and Study Characteristicsmentioning

confidence: 99%

“…• Trend for CBF DCS to underestimate CBF, especially at higher levels 2000; Brown et al, 2001Brown et al, , 2002Kurth et al, 2002;Ricci et al, 2006;Naulaers et al, 2007;Themelis et al, 2007;Zhou et al, 2009;Elliott et al, 2010Elliott et al, , 2014Alosh et al, 2016;Giovannella et al, 2020). Rodent models were relatively uncommon and were found in only five studies (De Visscher et al, 2003;Pryds et al, 2005;Carp et al, 2010;Shang et al, 2011;Hashem et al, 2022). Only one study was conducted in a canine model (Newton et al, 1997).…”

Section: Frontiers Inmentioning

confidence: 99%

“…This methodology requires sacrifice of the subject and were therefore limited to animal studies. Less invasive radiographic techniques were also commonly used in animal and human subjects including ASL-MRI (Huppert et al, 2006;Carp et al, 2010;Durduran et al, 2010;Wintermark et al, 2014;Alderliesten et al, 2017;Milej et al, 2020;Hashem et al, 2022), PW-MRI (Keller et al, 2003), fMRI-CBF (Alderliesten et al, 2014), CTP (Brown et al, 2001(Brown et al, , 2002Elliott et al, 2010Elliott et al, , 2014Taussky et al, 2012), XeCT (Kim et al, 2010), SPECT (Yamaguchi et al, 1999;Ogasawara et al, 2003;Murata et al, 2006;Schytz et al, 2009), and PET (Hock et al, 1997;Villringer et al, 1997;Saito et al, 2018;Giovannella et al, 2020;Polinder-Bos et al, 2020). Xenon 133 clearance based methods of determining CBF were also commonly utilized, especially in earlier studies (Pryds et al, 1990;Skov et al, 1991;Bucher et al, 1993;Kaminogo et al, 1995;Holzschuh et al, 1997;Rothoerl et al, 2003).…”

Section: Frontiers Inmentioning

confidence: 99%

“…This was likely attributable, in part, by the widespread availability of commercially produced CW-NIRS devices. Only 7 of the 28 CW-NIRS studies utilized a device developed in-house (Pryds et al, 1990(Pryds et al, , 2005Skov et al, 1991;Goddard-Finegold et al, 1998;Huppert et al, 2006;Kim et al, 2010;Hashem et al, 2022).…”

Section: Continuous Wave Nirsmentioning

confidence: 99%

“…Of note, not all studies found a positive correlation between CW-NIRS parameters and CBF. There were five studies included in this review where either no correlation was identified (Pellicer et al, 1999;Naulaers et al, 2007;Kim et al, 2010;Hashem et al, 2022) or a negative correlation was found between the CW-NIRS parameter and CBF (Ricci et al, 2006;Hashem et al, 2022).…”

Section: Continuous Wave Nirsmentioning

confidence: 99%

See 4 more Smart Citations

The Quantitative Associations Between Near Infrared Spectroscopic Cerebrovascular Metrics and Cerebral Blood Flow: A Scoping Review of the Human and Animal Literature

et al. 2022

View full text Add to dashboard Cite

Cerebral blood flow (CBF) is an important physiologic parameter that is vital for proper cerebral function and recovery. Current widely accepted methods of measuring CBF are cumbersome, invasive, or have poor spatial or temporal resolution. Near infrared spectroscopy (NIRS) based measures of cerebrovascular physiology may provide a means of non-invasively, topographically, and continuously measuring CBF. We performed a systematically conducted scoping review of the available literature examining the quantitative relationship between NIRS-based cerebrovascular metrics and CBF. We found that continuous-wave NIRS (CW-NIRS) was the most examined modality with dynamic contrast enhanced NIRS (DCE-NIRS) being the next most common. Fewer studies assessed diffuse correlation spectroscopy (DCS) and frequency resolved NIRS (FR-NIRS). We did not find studies examining the relationship between time-resolved NIRS (TR-NIRS) based metrics and CBF. Studies were most frequently conducted in humans and animal studies mostly utilized large animal models. The identified studies almost exclusively used a Pearson correlation analysis. Much of the literature supported a positive linear relationship between changes in CW-NIRS based metrics, particularly regional cerebral oxygen saturation (rSO2), and changes in CBF. Linear relationships were also identified between other NIRS based modalities and CBF, however, further validation is needed.

show abstract

Section: Search Results and Study Characteristicsmentioning

confidence: 99%

Section: Frontiers Inmentioning

confidence: 99%

Section: Frontiers Inmentioning

confidence: 99%

Section: Continuous Wave Nirsmentioning

confidence: 99%

Section: Continuous Wave Nirsmentioning

confidence: 99%

See 3 more Smart Citations

The Quantitative Associations Between Near Infrared Spectroscopic Cerebrovascular Metrics and Cerebral Blood Flow: A Scoping Review of the Human and Animal Literature

et al. 2022

View full text Add to dashboard Cite

show abstract

Magnetic resonance imaging approaches for studying mouse models of multiple sclerosis: A mini review

Gilli

Ceccarelli

2023

J of Neuroscience Research

View full text Add to dashboard Cite

Given that multiple sclerosis (MS) is a complex disease with an unclear etiology, a single animal model is unlikely to accurately represent all aspects of pathology and clinical features of the human condition. However, the availability of three major types of murine models of MS, that is, experimental autoimmune encephalomyelitis (EAE), viral models, and toxic models, enables studies of several relevant features of this debilitating disease. Researchers have recently begun to combine magnetic resonance imaging (MRI) technologies with other experimental strategies to acquire complementary information, for example, anatomical and functional, and study the effect of experimental manipulations longitudinally in a noninvasive way. This review summarizes the latest MRI studies investigating critical aspects of MS, such as atrophy, demyelination, neuroaxonal damage, and neuroinflammation, in mouse models of MS. Advanced techniques will be briefly discussed, providing references to specialized literature for the readers. Thus, this review aims to describe different imaging protocols used to study critical aspects of MS in a research laboratory, discussing the main related findings in the most significant murine models of the disease.

show abstract

Lactoferrin, chitosan double-coated oleosomes loaded with clobetasol propionate for remyelination in multiple sclerosis: Physicochemical characterization and in-vivo assessment in a cuprizone-induced demyelination model.

Abdelalim,

Elnaggar,

Abdallah

2024

International Journal of Biological Macromolecules

View full text Add to dashboard Cite

Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study

Cited by 11 publications

References 92 publications

The Quantitative Associations Between Near Infrared Spectroscopic Cerebrovascular Metrics and Cerebral Blood Flow: A Scoping Review of the Human and Animal Literature

The Quantitative Associations Between Near Infrared Spectroscopic Cerebrovascular Metrics and Cerebral Blood Flow: A Scoping Review of the Human and Animal Literature

Magnetic resonance imaging approaches for studying mouse models of multiple sclerosis: A mini review

Lactoferrin, chitosan double-coated oleosomes loaded with clobetasol propionate for remyelination in multiple sclerosis: Physicochemical characterization and in-vivo assessment in a cuprizone-induced demyelination model.

Contact Info

Product

Resources

About