Abnormal theta oscillation aggravated by chronic stress in the CA1 may mediate the deterioration of fear memory impairment induced by lipopolysaccharide

Mao, Min; Gao, Yu-Zhu; Yang, Jianjun; Zhou, Zhengdong; Ji, Mu‐Huo

doi:10.1016/j.brainresbull.2021.03.012

Cited by 6 publications

(2 citation statements)

References 27 publications

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“…Environmental enrichment was shown to affect the expression of genes associated with neuronal plasticity [8] and the transcription, translation, and regulation of related proteins [9]. Environmental enrichment can also positively affect neuronal survival [10], neuronal regeneration [11], formation and maturation of dendrites and dendritic spines, and functional integration [12]. Furthermore, an enriched environment can help improve learning and memory ability associated with hippocampal functions [13]; it can even help reduce the level of anxiety-like behaviors in experimental animals [14].…”

Section: Discussionmentioning

confidence: 99%

Bidirectional modulation of unimodal object recognition by stressful and enriched experiences in mice

Wang

Chen

et al. 2023

Stress and Brain

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Animals use cognitive behavior, by integrating information from multiple senses, to cope with the complex and changing environment. However, it is not yet understood how single sensory cognitive processes get modified and combined by multisensory cognition in these environments. To address this question, we exposed mouse to positive (tactile experience enrichment (TEE)) and negative (chronic restraint stress (CRS)) environments, and then studied how the dependence of their behavior on unimodal sensory (tactile or visual) processing was influenced by different environments. We found that TEE promoted object recognition behavior that depended on vision or tactile participation alone, whereas CRS impaired this dependence of behavior on single sensory channels. These results suggest that a positive environment promotes unimodal cognitive behavior, while the behavioral effect of negative environments is the opposite.

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Section: Discussionmentioning

confidence: 99%

Bidirectional modulation of unimodal object recognition by stressful and enriched experiences in mice

Wang

Chen

et al. 2023

Stress and Brain

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“…Subsequent studies used the social recognition paradigm [ 68 , 155 ], and we confirmed social memory impairment in our local colony as well [ 14 , 15 , 16 ]. However, AVP has a substantial effect on social behavior independently of memory formation [ 156 , 157 ]; therefore, to study memory formation, the novel object recognition (NOR) test seems to be a better choice. Previously we described NOR disturbance in our di/di animals [ 15 , 16 ].…”

Section: Memory Disturbances Associated With Improper Sleepmentioning

confidence: 99%

Vasopressin as a Possible Link between Sleep-Disturbances and Memory Problems

Török

Várga

Zelena

2022

IJMS

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Normal biological rhythms, including sleep, are very important for a healthy life and their disturbance may induce—among other issues—memory impairment, which is a key problem of many psychiatric pathologies. The major brain center of circadian regulation is the suprachiasmatic nucleus, and vasopressin (AVP), which is one of its main neurotransmitters, also plays a key role in memory formation. In this review paper, we aimed to summarize our knowledge on the vasopressinergic connection between sleep and memory with the help of the AVP-deficient Brattleboro rat strain. These animals have EEG disturbances with reduced sleep and impaired memory-boosting theta oscillation and show memory impairment in parallel. Based upon human and animal data measuring AVP levels, haplotypes, and the administration of AVP or its agonist or antagonist via different routes (subcutaneous, intraperitoneal, intracerebroventricular, or intranasal), V1a receptors (especially of hippocampal origin) were implicated in the sleep-memory interaction. All in all, the presented data confirm the possible connective role of AVP between biological rhythms and memory formation, thus, supporting the importance of AVP in several psychopathological conditions.

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TSPO activation ameliorates maternal immune activation induced PV interneuron deficits via BDNF/TrkB signaling

Mao,

Yu,

Liu

et al. 2024

Psychopharmacology

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Abnormal theta oscillation aggravated by chronic stress in the CA1 may mediate the deterioration of fear memory impairment induced by lipopolysaccharide

Cited by 6 publications

References 27 publications

Bidirectional modulation of unimodal object recognition by stressful and enriched experiences in mice

Bidirectional modulation of unimodal object recognition by stressful and enriched experiences in mice

Vasopressin as a Possible Link between Sleep-Disturbances and Memory Problems

TSPO activation ameliorates maternal immune activation induced PV interneuron deficits via BDNF/TrkB signaling

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