Abnormalities of the Electrogastrogram in Functional Gastrointestinal Disorders

Abstract

The electrogastrogram is abnormal in approximately 36% of functional dyspepsia patients and has a specificity of approximately 93%. Electrogastrography defines a subgroup of patients with functional dyspepsia and electrical rhythm disturbance. In irritable bowel syndrome, the electrogastrogram is usually abnormal only if concurrent dyspepsia is present.

Gastric myoelectrical activity abnormalities of electrogastrography in patients with functional dyspepsia

“…Also, there is limited information about the origin of the postprandial symptoms in patients with dysmotility-like FD (12,14). Although physiological abnormalities have been well documented in these studies, their relationship with the symptoms was not clearly described (5,12,24). However, studies on FD patients utilizing manometer and EGG have reported that antral hypomotility, changes in the electrical activity, and delayed gastric emptying are important mechanisms (6,8,12).…”

“…Gastric dysrhythmias can be detected by analyzing the EGG signal (1). Because it is more easily applicable than the other diagnostic techniques and is non-invasive, it is currently utilized in many fields for many conditions such as FD, pregnancy, anorexia nervosa, recurrent vomiting, and idiopathic and diabetic gastroparesis (5,9). Although much improvement has been made in the EGG field within the last twenty years, difficulties experienced in the recording of myoelectrical activity and analysis of the obtained signals still persist (9).…”

“…The pathogenesis of FD is not yet clearly known (5). Some genetic factors such as polymorphism or psychosocial factors or some other factors regarding bacterial flora are likely responsible for pathogenesis (2,5). Most of the patients with dyspeptic complaints of unknown cause were found to have various gastric and duodenal motility abnormalities leading to antral hypomotility (6,7), gastric motor abnormalities due to abnormal gastric myoelectrical activity, and delayed gastric emptying (8).…”

“…Epidemiological studies have reported a similar incidence of functional gastrointestinal diseases in Europe and the United States of America (USA) and a lower incidence of such diseases in Asia (4). The pathogenesis of FD is not yet clearly known (5). Some genetic factors such as polymorphism or psychosocial factors or some other factors regarding bacterial flora are likely responsible for pathogenesis (2,5).…”

Prevalence of Gastric Motility Disorders in Patients with Functional Dyspepsia

“…Moreover, the results of many previous studies in gastric motility abnormalities have identified a variety of abnormalities, including delayed gastric emptying, 4,17,18 adaptive relaxation disorder, 5 intragastric food distribution abnormalities, [19][20][21] postprandial antral dysmotility, 22 gastric electrical activity abnormalities, [23][24][25] decreased interdigestive migrating contractions, 26,27 and postprandial hypercontraction of the gastric fundus. 29 According to reports, adaptive relaxation disorders and delayed gastric emptying are particularly associated with upper gastrointestinal symptoms.…”