ABO Blood Type Is Associated with Thrombotic Risk in Patients with Nonvalvular Atrial Fibrillation

Jang, Albert Youngwoo; Seo, Jeongduk; Park, Yae Min; Shin, Yong Hoon; Lee, Joonpyo; Oh, Pyung Chun; Kang, Woong Chol; Chung, Wook‐Jin; Moon, Jeonggeun

doi:10.3390/jcm11113064

Cited by 2 publications

(1 citation statement)

References 39 publications

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“…Additionally, most AB patients were diabetic (p = 0.049). This study might be in line with studies demonstrated an higher thrombotic risk in ABpatients with non-valvular atrial fibrillation (31), as well as a higher incidence of cardiovascular diseases in non-0 patients (32), which may induces renal failure. The present study is not devoid of limitations.…”

Section: Discussionsupporting

confidence: 91%

AB0 blood groups and oncological and functional outcomes in bladder cancer patients treated with radical cystectomy

Tafuri

Panunzio

Soldano

et al. 2022

Arch Ital Urol Androl

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Objectives: We investigated AB0 blood groups prevalence according to preoperative and pathological tumor characteristics, and their association with oncological outcomes, and renal function decline in a contemporary large cohort of bladder cancer (BCa) patients, who underwent radical cystectomy (RC) at a tertiary referral center. Materials and Methods: We retrospectively evaluated data of patients with histologically confirmed and clinically non metastatic BCa, who underwent RC between 2014 and 2021 at our Institution. Kaplan-Meier (KM) plots and Cox regression (CR) models tested the relationship between AB0 blood groups and local recurrence-, metastasis-, cancer specific mortality-, and overall mortality-free survival. Logistic regression (LR) models tested the association between AB0 blood groups and renal function decline, defined as an estimated Glomerular Filtration Rate (eGFR) < 60 mL/min, at post-operative day 1, discharge and 6- months of follow-up. Results: Of 301 included patients, 128 (42.5%) had group A, 126 (41.9%) had group 0, 28 (9.3%) had group B, and 19 (6.3%) had group AB. Patients with group 0 developed higher rates of muscle- invasive BCa (p = 0.028) with high-grade features (p = 0.005) at last bladder resection, and less frequently received preoperative immunotherapy with Bacillus of Calmette-Guerin (p = 0.044), than their non-0 counterparts. Additionally, these patients harbored more advanced pathologic tumor stage at RC (p = 0.024). KM plots showed no differences among all tested cancer control outcomes between AB0 blood groups (p > 0.05 in all cases). Patients with group AB presented the lowest median eGFR at each time point. In multivariable LR analyses addressing renal function decline, group AB was independently associated with eGFR< 60 mL/min at discharge (Odds Ratio: 4.28, p = 0.047). Conclusions: Among AB0 blood groups, patients with group 0 exhibited the most aggressive tumor profile. However, no differences were recorded in recurrence or survival rates. Group AB independently predicted renal function decline at discharge.

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Section: Discussionsupporting

confidence: 91%

AB0 blood groups and oncological and functional outcomes in bladder cancer patients treated with radical cystectomy

Tafuri

Panunzio

Soldano

et al. 2022

Arch Ital Urol Androl

View full text Add to dashboard Cite

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AB0 and Rh Blood Groups as a Predictors of Infarct Etiology in Ischemic Stroke: Insights from a Retrospective Analysis

Dikbas,

Tonkaz

2024

Preprint

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Objective AB0 blood group antigens has shown to be linked with coagulopathy. In this context, this study was conducted to investigate the relationship between AB0 and Rhesus (Rh) blood groups with ischemic stroke on the basis of infarct etiology and trial of ORG 10172 in acute stroke treatment (TOAST) classification. Methods The population of this retrospective case-control study was consisted of 264 patients with ischemic stroke between January 2021 and December 2023. Patients’ stroke etiologies based on TOAST classification, serum biochemical data, brain and neck computed tomography angiograms, AB0 and Rh blood groups were obtained from their electronic medical records. Results We compared large vessel atherosclerosis (LVA) with all other etiologies in the TOAST classification. AB blood type was observed more frequently in patients with LVA than all other AB0 blood types combined (p = 0.049). Conclusions We observed stroke due to LVA more frequently in patients of advanced age and AB blood type compared to other patients. Our findings suggest that AB blood type may also be a risk factor in addition to known stroke risk factors.

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ABO Blood Type Is Associated with Thrombotic Risk in Patients with Nonvalvular Atrial Fibrillation

Cited by 2 publications

References 39 publications

AB0 blood groups and oncological and functional outcomes in bladder cancer patients treated with radical cystectomy

AB0 blood groups and oncological and functional outcomes in bladder cancer patients treated with radical cystectomy

AB0 and Rh Blood Groups as a Predictors of Infarct Etiology in Ischemic Stroke: Insights from a Retrospective Analysis

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