Abscesos hepáticos piógenos

Pérez, Julio C.; Cernuda, R.F. Baldonedo; González, Juan José; Álvarez, Luis

doi:10.1016/s0009-739x(01)71869-6

Cited by 7 publications

(1 citation statement)

References 126 publications

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“…The treatment of Clostridium septicum bacteremia consists of early broad-spectrum antibiotic therapy and surgical debridement [7,8]. Blood cultures should be obtained promptly to achieve a timely diagnosis and aid in future antibiotic regimens.…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Pneumoperitoneum and Gas-Forming Liver Abscesses as Initial Signs of Colorectal Liver Metastases

Vázquez-MeleroAlba

CarrilloMaitane

AretxabalaIzaskun

et al. 2017

Surgical Infections Case Reports

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Background: Clostridium septicum is a gram-positive, anaerobic, spore-forming bacilli found in the gastrointestinal tract. It rarely causes spontaneous infections that are associated with high mortality. Association of Clostridium infection with colorectal malignancies or immunosuppression have been reported previously, tumors of the ascending colon are described in most cases. The anaerobic glycolysis of the tumor produces an acidic, hypoxic environment favoring mucosal ulceration and bowel into bloodstream translocation, leading to fulminant sepsis, infected liver metastases, and hollow viscous perforation presenting as pneumoperitoneum. Case Presentation: We report a case of a 61-year-old male with type 2 diabetes mellitus and chronic lymphocytic leukemia who presented with five-day generalized abdominal pain and fever. His symptoms were caused by colon cancer with liver metastases infected with Clostridium septicum. The clinical outcome and management of the case is reported. Conclusion: In patients with hematologic or colorectal cancer and gas-forming liver abscesses, the possibility of Clostridium septicum infection and metastatic cancers should be considered. The aim of this case is to stress the importance of maintaining a high suspicion of Clostridium septicum infection in patients with underlying colonic malignancy.

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Section: Discussion and Literature Reviewmentioning

confidence: 99%