Absence of mitotic reduction in regenerating rat livers exposed to ultrasound

Miller, Morton W.; Kaufman, Gary E.; Cataldo, Frederick L.; Carstensen, Edwin L.

doi:10.1002/jcu.1870040304

Cited by 10 publications

(2 citation statements)

References 11 publications

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“…However, this observation was not able to be confirmed under virtually the identical research protocol, even when the SATA ultrasonic intensity ranged from 60 mW/cm2 up to 16 W/cm2 (Miller et al, 1976).…”

Section: Experimental Studies Of Ultrasound Bioeffects: Some General mentioning

confidence: 51%

“…A significant reduction in the frequency of mitotic cells in surgically stimulated rat liver from diagnostic level, continuous wave ultrasound (SATA intensity: 60 mW/cm2) was reported (Kremkau and Witkofski, 1974). However, this observation was not able to be confirmed under virtually the identical research protocol, even when the SATA ultrasonic intensity ranged from 60 mW/cm2 up to 16 W/cm2 (Miller et al, 1976).…”

Section: Experimental Studies Of Ultrasound Bioeffects: Some General mentioning

confidence: 99%

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Ultrasonic Bioeffects: A View of Experimental Studies

O’Brien

1984

Birth

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Diagnostic ultrasound of the pulse-echo imaging type is used in at least 25 per cent of pregnancies, and Doppler continuous wave ultrasound, as employed in external electronic fetal monitors, is used in nearly all pregnancies. Diagnostic ultrasound energy levels are from 0.1 to 40 m Wlcm'. These intensity levels depend on the characteristics of the ultrasonic beam and temporal exposure. The American Institute of Ultrasound in Medicine states that. . . "there have. been as of October, I982 no independently confirmed significantbiological effects in mammalian tissues exposed to intensities below I00 m W/cm2."Some of the animal studies reviewed by the AIUM to reach this conclusion are discussed. (BIRTH 11:3, 1984)

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Section: Experimental Studies Of Ultrasound Bioeffects: Some General mentioning

confidence: 51%

Section: Experimental Studies Of Ultrasound Bioeffects: Some General mentioning

confidence: 99%

Ultrasonic Bioeffects: A View of Experimental Studies

O’Brien

1984

Birth

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Compilation of reported biological effects data and ultrasound exposure levels

Stewart¹,

Stewart²,

Moore³

et al. 1985

J of Clinical Ultrasound

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A compilation of reports of biological effects and related ultrasound exposure levels can be useful in the identification of trends in effects data that may be developing in the literature. The exposures in the experiments reviewed were at frequencies used in medicine. For short (10 minutes or less) continuous wave exposure, with the exception of behavioral effects where variable results have been observed, this tabulation did not identify any in vivo or in vitro effects at spatial peak, temporal average (SPTA) intensities less than 100 mW/cm2. However, a number of effects using pulsed sources with SPTA intensities under this level have been reported. There are several frequently recurring topics in recent reports which include developmental effects and microstructure changes at the cellular level. In addition to animal investigations, there are some limited human epidemiological studies reporting an association between medical ultrasound exposure in utero and developmental effects. Although sufficient research has not been completed to draw conclusions, the findings deserve further investigation. A systematic pattern of directed research on a large scale is not apparent. The available data consist of many scattered studies conducted by individual investigators and groups throughout the world.

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Selected Biological Effects of Ultrasound

Dunn

1982

Essentials of Medical Ultrasound

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Absence of mitotic reduction in regenerating rat livers exposed to ultrasound

Cited by 10 publications

References 11 publications

Ultrasonic Bioeffects: A View of Experimental Studies

Ultrasonic Bioeffects: A View of Experimental Studies

Compilation of reported biological effects data and ultrasound exposure levels

Selected Biological Effects of Ultrasound

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