Absorbed dose to the bladder from<sup>99</sup>Tc<sup>m</sup>DTPA

Diffey, B. L.; Hilson, A. J.W.

doi:10.1259/0007-1285-49-578-196

Cited by 8 publications

(7 citation statements)

References 16 publications

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“…An optimum micturition volume also exists which, combined with the optimum injection time, minimizes the radiation dose for each hydration scheme. As the dependence of the minimal dose value on the micturition volume is weak, especially for V1 x 2 schemes, it is suggested that under controlled hydration conditions there is no need for the patient to void frequently, as was previously proposed (Diffey and Hilson 1976;Unnikrishnan 1974), but to void at certain time intervals which may be determined by the applied hydration protocol. Anyway, man is able to void at any degree of bladder filling (Muellner 1960).…”

Section: Discussionmentioning

confidence: 91%

“…According to the model of Diffey and Hilson (1976), the exposure rate due to photon radiation at some time t on the surface of the spherical bladder (taR.rain-I), including attenuation of the beam due to absorption and scattering within the sphere, is given by:…”

Section: Appendixmentioning

confidence: 99%

“…Among the precautions proposed for the radiation protection of the bladder, those of a good hydration of the patient, encouragment to void frequently and a bladder which is as full as reasonably possible at the time of injection predominate (Diffey and Hilson 1976). These measures were predicted by dynamic models for bladder dosimetry, which assume a constant average urine flow rate to the bladder.…”

mentioning

confidence: 99%

“…Giving due consideration to these data, we modified a previously proposed dynamic model for the estimation of the dose to the bladder walls in the 99mTc-DTPA renal dynamic study (Diffey and Hilson 1976), to find a more realistic theoretical approach to the conditions under which the phenomenon of bladder filling takes place.…”

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confidence: 99%

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The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

et al. 1992

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A spherical bladder dynamic model for the estimates of the radiation dose to the bladder walls from intravenously injected radionuclides was implemented to investigate in theory the effect of hydration on the reduction of the bladder dose in technetium-99m diethylene triamine penta-acetic acid (99mTc) DTPA renography. This model gives due consideration to the variation with time of the urine flow rate to the bladder, following a known fluid load. According to the model, the estimated dose depends on the renal function, the fluid load, the time elapsed from the fluid load to the i.v. DTPA injection, the micturition volume and the residual urine volume. Experimental data concerning the values of these parameters for normal individuals were obtained from the literature. Calculations cover the time period from i.v. injection up to the time of the ninth postinjection void. Results show that the patient's condition of hydration is critical for the radiation protection of the bladder. It is shown that optimum combinations of the values of the parameters involved in the calculations exist, which minimize the radiation dose. On the basis of these results, a general protocol is proposed, referring to the hydration conditions under which the renal dynamic study may be normally carried out, with a minimal absorbed dose to the bladder walls (less than 0.045 mGy/MBq).

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Section: Discussionmentioning

confidence: 91%

Section: Appendixmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

et al. 1992

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“…This approach will minimize exposure to radiation regardless of the level of renal function, administration of furosemide, or presence of an obstructed kidney. 30,103,106 …”

Section: Radiation Safety In Imagingmentioning

confidence: 99%

SNMMI Procedure Standard/EANM Practice Guideline for Diuretic Renal Scintigraphy in Adults With Suspected Upper Urinary Tract Obstruction 1.0

Taylor

Brandon

Palma

et al. 2018

Seminars in Nuclear Medicine

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Radiation dose to the bladder wall and the gonads from direct radionuclide cystography in children

Dimitriou¹,

Fretzayas²,

Nicolaidou³

et al. 1987

Eur J Nucl Med

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A dynamic spherical bladder model, previously developed in our laboratory, was implemented to evaluate the absorbed dose to the bladder wall from 99mTc-pertechnetate and direct radionuclide cystography (DRC). This model takes into account the flow rate of normal saline into the bladder and the bladder volume as a function of the filling time. The DRC examinations of 36 children were analysed and calculations were carried out in order to estimate (a) the absorbed dose to the bladder during and following the DRC examination and (b) the gonadal dose. It is shown that the estimated dose to the bladder wall is much greater than that estimated by static models. It is also shown that the absorbed dose to the bladder due to the activity in the residual urine following the examination is even greater than the dose received during the DRC procedure. Our results indicate that in order to reduce the radiation burden, besides the so far proposed precautions, concerning the shortening of the DRC procedure, the patient should also be well hydrated and encouraged to void frequently after the examination.

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Absorbed dose to the bladder from⁹⁹Tc^mDTPA

Cited by 8 publications

References 16 publications

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

SNMMI Procedure Standard/EANM Practice Guideline for Diuretic Renal Scintigraphy in Adults With Suspected Upper Urinary Tract Obstruction 1.0

Radiation dose to the bladder wall and the gonads from direct radionuclide cystography in children

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Absorbed dose to the bladder from99TcmDTPA

Cited by 8 publications

References 16 publications

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

The effect of hydration on the dose to the urinary bladder wall during technetium-99m diethylene triamine penta-acetic acid renography

SNMMI Procedure Standard/EANM Practice Guideline for Diuretic Renal Scintigraphy in Adults With Suspected Upper Urinary Tract Obstruction 1.0

Radiation dose to the bladder wall and the gonads from direct radionuclide cystography in children

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Absorbed dose to the bladder from⁹⁹Tc^mDTPA