Abstract:Introduction MicroRNAs (miRNAs) are small non-coding RNAs which are known to play an important role in proliferation, differentiation, invasion and angiogenesis of different malignant tumors. The role of tissue and blood level of miRNAs as useful bio-markers of gliomagenesis is also increasing. Interest is growing on tissue and plasma miR-222 level as prognostic marker in first line chemo- and radiotherapy treated patients with glioma, the mechanisms of action and the target genes of this miRNA in gliomagenesi… Show more
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