Accelerated cell-type-specific regulatory evolution of the human brain
Dennis Joshy,
Gabriel Santpere,
Soojin V. Yi
Abstract:The molecular basis of human brain evolution is a key piece in understanding the evolution of human-specific cognitive and behavioral traits. Comparative studies have suggested that human brain evolution was accompanied by accelerated changes of gene expression (referred to as “regulatory evolution”), especially those leading to an increase of gene products involved in energy production and metabolism. However, the signals of accelerated regulatory evolution were not always consistent across studies. One confo… Show more
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