Accelerated healing with the use of a silk fibroin membrane for the guided bone regeneration technique

Song, Ji-Young; Kim, Seong‐Gon; Lee, Jun Young; Chae, Weon‐Sik; Kweon, HaeYong; Jo, You‐Young; Lee, Kwang-Gill; Lee, Yong-Chan; Choi, Je‐Yong; Kim, Jwa-Young

doi:10.1016/j.tripleo.2011.05.002

Cited by 55 publications

(56 citation statements)

References 26 publications

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“…In a previous study we showed that using SFM as a barrier had a positive effect on GBR in a bone defect. SFM contributed to new bone formation in a rabbit calvarial defect model compared to the uncovered control (Song et al 2011). However, clinical application of SFM Silk membrane plus 3% 4-hexylresorcinol (3% 4-HR + SM), collagen membrane (CM).…”

Section: Discussionmentioning

confidence: 99%

“…Because of its superior mechanical properties (Gosline et al 1986), it is used in biomedical application such as drug-delivery devices, tissue engineering scaffolds, vessels, and artificial tympanic membranes (Sofia et al 2000;Arai et al 2003, Kim et al 2004, Kim et al 2010. Previously study have shown that SM facilitates new bone formation in artificial bone defects (Song et al 2011;. Alkylresorcinols are natural non-isoprenoid lipids with antioxidant and antimutagenic properties that are found in various plants and microorganisms (Kozubek et al 1999).…”

Section: Animals and Surgical Proceduresmentioning

confidence: 99%

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The Effect of Silk Membrane Plus 3% 4-hexylresorcinol on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

Seok¹,

Lee²,

Kim³

et al. 2013

International Journal of Industrial Entomology

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The objective of this study was to evaluate the bone regeneration capability of silk membrane plus 3% 4-hexylresorcinol (3% 4-HR plus SM) in a rabbit calvarial defect model. Twenty New Zealand white rabbits were used in this study. Bilateral round shaped defects were created in the parietal bone (diameter: 8.0 mm). And the defects were covered with (1) 3% 4-HR plus SM, (2) collagen membrane (CM), (3) no graft material. After surgery, the animals were sacrificed at 4 weeks and 8 weeks. Bone regeneration was analyzed in each section by micro-computerized tomography (μ-CT). And Hematoxylin and eosin stains were used for histological analysis. As measured by μ-CT analysis 4 weeks after surgery, the average of new bone formation in animals treated with 3% 4-HR plus SM was greater than that of animals treated with CM. and the difference was statistically significant. And well organized lamella bones were observed in the histological view of the 3% 4-HR plus SM group. Therefore, more bone regeneration was seen in animals treated with 3% 4-HR plus SM than in those treated with CM or uncovered control.

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Section: Discussionmentioning

confidence: 99%

Section: Animals and Surgical Proceduresmentioning

confidence: 99%

The Effect of Silk Membrane Plus 3% 4-hexylresorcinol on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

Seok¹,

Lee²,

Kim³

et al. 2013

International Journal of Industrial Entomology

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“…Similar behaviors and trends with more variations were detected for all samples after exposing to artificial day light for 160 h (Figure 2b). Figure 3 shows the reflectance % spectra in the visible region for unexposed undyed and neem dyed (a) as well as exposed (b) silk fabrics dyed in a medium of pH = 6 and time of dying 60 minutes at different dye bath temperatures (20,40,60, and 80 ºC). It was clear from the figure that the behaviors of the unexposed and exposed dyed silk fabrics completely change in comparison with the undyed fabric.…”

Section: Optical Parametersmentioning

confidence: 99%

Study the effect of different dyeing conditions of extracted natural dye from leaves of neem on silk fabrics

Abdel-Zahe¹,

Moselhey²,

Guirguis³

2018

J.Chem.Metrol.

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The aim of the present work was to evaluate the effect of artificial day light for 160 h on silk fabrics dyeing with different conditions such as; different dye bath pH values, different dyeing temperatures, and different dyeing times; of extracted natural dye from Azadirachta indica (neem) leaves. The reflectance spectra of the untreated and treated silk fabrics were followed using spectrophotometer technique. The effects of dyeing conditions in the optical parameters, such as; CIE tristimulus values, color parameters, absorption coefficient as well as extinction coefficient and color strength, were determined before and after exposure. The obtained results indicate that the silk fabrics were found to be highly dependent on either of these different dyeing conditions and/or artificial day light exposure. Also, variations in the values of the optical band gap energy were detected. Improvement in the dyeing process were produced which may be attributed to the induced structural change due to the variation in the chemical bonds in silk fabrics. The present work gives the chance to produce a new traditional natural dye to meet the environmental future demands technology of high quality fantastic dyed pattern.

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“…Recently, silk fibroin (SF) has attracted the attention of researchers because it has good blood compatibility (Sakabe et al, 1989;Um et al, 2002) and excellent cytocompatibility (Minoura et al, 1995). Owing to these useful properties, SF has been studied for biomedical applications including artificial bone substitute , wound dressing (Lee et al, 2014), tympanic membrane (Kim et al, 2010), and membrane for guided regeneration (Song et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Storage stability of silk solution for viscosity and electrospinnability

Kim¹,

Um²

2016

International Journal of Industrial Entomology

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Accelerated healing with the use of a silk fibroin membrane for the guided bone regeneration technique

Cited by 55 publications

References 26 publications

The Effect of Silk Membrane Plus 3% 4-hexylresorcinol on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

The Effect of Silk Membrane Plus 3% 4-hexylresorcinol on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

Study the effect of different dyeing conditions of extracted natural dye from leaves of neem on silk fabrics

Storage stability of silk solution for viscosity and electrospinnability

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