2024
DOI: 10.1002/cam4.7033
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Access to innovative therapies in pediatric oncology: Report of the nationwide experience in Canada

Sandra Judd,
Gabriel Revon‐Riviere,
Stephanie A. Grover
et al.

Abstract: BackgroundThe need for new therapies to improve survival and outcomes in pediatric oncology along with the lack of approval and accessible clinical trials has led to “out‐of‐trial” use of innovative therapies. We conducted a retrospective analysis of requests for innovative anticancer therapy in Canadian pediatric oncology tertiary centers for patients less than 30 years old between 2013 and 2020.MethodsInnovative therapies were defined as cancer‐directed drugs used (a) off‐label, (b) unlicensed drugs being us… Show more

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