Accuracy and reliability of continuous blood glucose monitor in post‐surgical patients

Abstract

Background: The STG‐22™ is the only continuous blood glucose monitoring system currently available. The aim of this study is to determine the accuracy and reliability of the STG‐22™ for continuously monitoring blood glucose level in post‐surgical patients. Methods: Fifty patients scheduled for routine surgery were studied in surgical intensive care unit (ICU) of a university hospital. After admission to the ICU, the STG‐22™ was connected to the patients. An attending physician obtained blood samples from a radial arterial catheter. Blood glucose level was measured using the ABL™800FLEX immediately after blood collection at 0, 4, 8, and 16 h post‐admission to the ICU (total of 200 blood glucose values). Results: The correlation coefficient (R2) was 0.96. In the Clarke error grid, 100% of the paired measurements were in the clinically acceptable zone A and B. The Bland and Altman analysis showed that bias±limits of agreement (percent error) were 0.04(0.7)±0.35(6.3) mmol (mg/dl) (7%), −0.11(−2)±1.22(22) (15%) and −0.33(−6)±1.28(23) (10%) in hypoglycemia (<70(3.89) mmol (mg/dl), normoglycemia (3.89(70)–10(180) mmol (mg/dl), and hyperglycemia (>10(180) mmol (mg/dl), respectively. Conclusions: The STG‐22™ can be used for measuring blood glucose level continuously and measurement results are consistent with intermittent measurement (percentage error within 15%). Therefore, the STG‐22™ is a useful device for monitoring in blood glucose level in the ICU for 16 h.

Impact of newly developed, next-generation artificial endocrine pancreas

“…The multichannel pump and the glucose sensor electrode both had an accuracy of !5%. The accuracy and reliability of this system during and after surgery have been confirmed (15,16). In this study, the results using STG-55 were similar to those obtained with the conventional artificial pancreas (STG-22).…”

Usefulness of artificial endocrine pancreas during resection of insulinoma

“…STG-22 is capable of measuring the blood glucose level continuously with its glucose sensor, and automatically infuses insulin and/or glucose to adjust the blood glucose level in accordance with a target glucose value, which is called a closed-loop system. The perioperative accuracy and reliability of continuous blood glucose monitoring during use of an artificial pancreas have been established, both intraoperatively (21) and postoperatively (22). In this case, STG-22 was shown to be safe and efficient in a patient with insulinoma during and after surgery, similarly to other reports.…”

Perioperative insulin therapy using a closed-loop artificial endocrine pancreas after hepatic resection

“…The STG-22 system is a reliable and accurate device that measures blood glucose concentrations continuously and is comparable to the ABL 800FLEX machine (Radiometer Medical ApS, Brønshøj, Denmark) recommended by the National Committee for Clinical Laboratory Standards [22,23] . The STG-22 closed-loop glycemic control system is composed of a glucose sensor for the detection and/or monitoring of glucose and pumps for the infusion of appropriate amounts of insulin or glucose [24,25] .…”