Accuracy of 64-Slice Computed Tomography to Classify and Quantify Plaque Volumes in the Proximal Coronary System

Leber, Alexander; Becker, Alexander; Knez, Andreas; Ziegler, Franz von; Sirol, Marc; Nikolaou, Konstantin; Ohnesorge, Bernd; Fayad, Zahi A.; Becker, Christoph; Reiser, Maximilian; Steinbeck, Gerhard; Boekstegers, Peter

doi:10.1016/j.jacc.2005.10.058

Cited by 666 publications

(273 citation statements)

References 20 publications

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“…Currently, 15 studies have examined 64-slice technology for the evaluation of suspected CAD (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21) (Figure 2). In these studies, 64-slice MDCT was able to assess 97% of all coronary artery segments visualized by both CCA and MDCT (Table 1), which is approximately 5% more than previous 16-slice technology.…”

Section: Assessment Of Significant Cad Using Mdctmentioning

confidence: 99%

“…Furthermore, when using patient-based analysis, defined as the presence of one or more significant coronary artery lesions in a study subject, sensitivity for 64-slice MDCT ranged between 88% to 100% in the 15 studies reviewed (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). Additionally, in study populations with a low prevalence of CAD (32%), per-patient sensitivity remained very high (96%) (9).…”

Section: Assessment Of Significant Cad Using Mdctmentioning

confidence: 99%

See 1 more Smart Citation

Transitioning from 16-slice to 64-slice multidetector computed tomography for the assessment of coronary artery disease: Are we really making progress?

Khan

Rawal

Eisenberg

2009

Canadian Journal of Cardiology

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Section: Assessment Of Significant Cad Using Mdctmentioning

confidence: 99%

Section: Assessment Of Significant Cad Using Mdctmentioning

confidence: 99%

Transitioning from 16-slice to 64-slice multidetector computed tomography for the assessment of coronary artery disease: Are we really making progress?

Khan

Rawal

Eisenberg

2009

Canadian Journal of Cardiology

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“…Proximal course of the coronary arteries is readily imaged and assessment of distal coronary stenosis can be performed. High correlation has been found when compared with ICA and intracoronary ultrasound results for the defi nition of coronary artery disease (Leber et al 2005(Leber et al , 2006Mollet et al 2005). In this article, we aimed to examine the use of 64 slice CT for the evaluation of various anomalous coronary arteries.…”

Section: The 64-slice Ct Scanning Techniquementioning

confidence: 97%

Contrast-Enhanced 64-Slice Computed Tomography in Detection and Evaluation of Anomalous Coronary Arteries

Karaca

Kirilmaz

Öncel

et al. 2007

Tohoku J. Exp. Med.

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Anomalous coronary artery (ACA) has either an unusual origin or different anatomical course and is associated with sudden cardiac death. The absence or nonspecifi c symptoms of ACA make its diagnosis diffi cult. Mostly, ACA is diagnosed coincidentally during invasive coronary angiogram (ICA). A conventional computed tomography (CT) cannot provide detailed images of coronary arteries of the moving heart, but 64-slice CT, with its short acquisition time, can provide detailed anatomy of coronary arteries non-invasively. In this study, we assessed the validity of contrast-enhanced 64-slice CT in the evaluation of ACA. ICA was performed in 7,574 patients for the diagnosis or evaluation of occlusive coronary artery disease and detected coronary anomalies in 56 patients (0.7%). We then performed 64-slice CT in 53 patients out of the 56 patients with demonstrated or suspected coronary anomaly, showing the origin and the course of the ACA along with stenosis, except for one patient who could not be evaluated due to image distortion artifacts. Contrast-enhanced 64-slice CT was also performed in 374 patients with vague signs and symptoms, detecting coronary anomalies in 7 patients (1.2%). Thus, in the total of 59 patients undergone 64-slice CT, we were able to visualize the entire abnormal coronary tree with a high diagnostic image quality. This is the fi rst study to demonstrate the utility of 64-slice CT in a large series of ACA. Contrast-enhanced 64-slice CT is superior to ICA to identify the presence and course of ACA and should be the fi rst line diagnostic tool in the evaluation of ACA.coronary artery anomaly; 64-slice computed tomography

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“…A identificação desses elementos e do estágio evolutivo das lesões poderá contribuir na escolha da estratégia terapêutica não só medicamentosa como invasiva, selecionando pacientes de maior risco. [18][19][20] Alguns pacientes avaliados neste trabalho foram previamente submetidos a procedimentos de revascularização do miocárdio. A possibilidade de reestenose intrastent tem estimulado a avaliação não-invasiva do stent pela angiotomografia coronária com múltiplos detectores, e em alguns estudos esse método poderia auxiliar na avaliação dessa complicação.…”

Section: Número De % Pacientesunclassified

Padrões de indicação da angiotomografia coronária de múltiplos detectores na prática clínica: experiência de um centro de referência

Martins¹,

Yordi²,

Quadros³

et al. 2010

Rev. Bras. Cardiol. Invasiva

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RESUMOIntrodução: A angiotomografia coronária com múltiplos detectores está sendo progressivamente utilizada na prá-tica clínica diária. Não existem estudos em nosso meio analisando o perfil dos pacientes submetidos a esse exame. Método: Estudo de coorte transversal, incluindo pacientes submetidos a angiotomografia coronária com múl-tiplos detectores em um centro de referência por indicação de seu médico assistente. Antes da realização do exame, foram avaliadas a presença de fatores de risco, a apresentação clínica da doença arterial coronária e os exames diagnósticos não-invasivos e invasivos já realizados. Os dados foram analisados com o programa SPSS 13.0. Resultados: A média de idade dos 689 pacientes incluídos foi de 63,7 anos e 52% eram do sexo masculino. Em relação aos fatores de risco, 65% eram hipertensos, 17% eram diabéticos, 9,6% eram fumantes ativos e 63% apresentavam história familiar de doença arterial coronária. Quanto à apresentação clínica, 49% dos pacientes eram assintomáticos, 16% apresentavam dor torácica atípica e 35%, angina. Em relação à avaliação diagnóstica prévia, 25% realizaram ecocardiograma e 21% realizaram cintilografia, e 37% dos pacientes não haviam realizado nenhum desses exames. Menos de 1% dos pacientes encaminhados não apresentava nenhuma dessas características, e a maioria apresentava três ou mais fatores de risco, sendo frequente a combinação dessa característica com exames diagnós-ticos alterados e história de revascularização prévia. Entre os pacientes assintomáticos, 98% apresentavam algum fator de risco e 27% tinham algum exame prévio positivo. Conclusão: A maioria dos pacientes encaminhados para angiotomografia coronária com múltiplos detectores ABSTRACT Multidetector Computed Tomographic Angiography of Coronary Arteries in Daily Clinical Practice: Experience of a Tertiary CenterBackground: Multidetector computed tomographic angiography of coronary arteries has been increasingly used in the daily clinical practice. There are no studies in Brazil analyzing the profile of patients submitted to this new test. Method: Cross-sectional cohort study including patients submitted to multidetector computed tomographic angiography at a reference center and referred by their attending physician. Before angiotomographic evaluation, patients were assessed for the presence of risk factors, clinical presentation and previous results of invasive and non-invasive tests. Data were analyzed using SPSS 13.0. Results: Mean age of the 689 patients was 63.7 years and 52% were men. As to risk factors, 65% were hypertensive, 17% were diabetic, 9.6% were smokers, and 63% had family history of coronary artery disease. As to the clinical presentation of the disease, 49% were asymptomatic, 16% had atypical chest pain and 35% had angina. Twenty-five percent of the patients had echocardiography, 21% had myocardial scintigraphy and 37% had no previous tests. Less than 1% of the patients did not have any of these characteristics and most of them had three or more risk factors, frequently associated to a...

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Accuracy of 64-Slice Computed Tomography to Classify and Quantify Plaque Volumes in the Proximal Coronary System

Abstract: We conclude that 64-slice CT reveals encouraging results to noninvasively detect different types of coronary plaques located in the proximal coronary system. The ability to determine plaque burden currently is hampered by mainly an insufficient reproducibility.

Cited by 666 publications

References 20 publications

Transitioning from 16-slice to 64-slice multidetector computed tomography for the assessment of coronary artery disease: Are we really making progress?

Transitioning from 16-slice to 64-slice multidetector computed tomography for the assessment of coronary artery disease: Are we really making progress?

Contrast-Enhanced 64-Slice Computed Tomography in Detection and Evaluation of Anomalous Coronary Arteries

Padrões de indicação da angiotomografia coronária de múltiplos detectores na prática clínica: experiência de um centro de referência

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