Accuracy of Sentinel Lymph Node Biopsy for Inguinal Lymph Node Staging of Penile Squamous Cell Carcinoma: Systematic Review and Meta-Analysis of the Literature

Abstract

Sentinel lymph node mapping in penile squamous cell carcinoma is a method with a high detection rate and sensitivity. Using radiotracer and blue dye for sentinel lymph node mapping and including only cN0 disease ensures the highest detection rate and sensitivity.

Feasibility of Intraoperative Navigation to the Sentinel Node in the Groin Using Preoperatively Acquired Single Photon Emission Computerized Tomography Data: Transferring Functional Imaging to the Operating Room

“…However, the recent meta-analysis of 19 studies by Sadeghi et al revealed a pooled detection rate of 90% using current techniques, suggesting that there is still room for improvement. 16 Since the reliability of SN biopsy depends on successful preoperative, intraoperative and postoperative identification of all tumor positive SNs, it may be hypothesized that refining the intraoperative procedure using a combination of new technologies is likely to contribute to a higher detection rate and a lower false-negative rate in the future. However, further validation of surgical navigation technology in larger, randomized trials is required to substantiate this assumption.…”

Sentinel node biopsy for lymph nodal staging of uterine cervix cancer: A systematic review and meta-analysis of the pertinent literature

“…7,8,86,107 It seems that the algorithm proposed by Cormier et al can maximize the sensitivity in the sentinel node mapping of uterine cervical cancers.…”

Lymphatic mapping and sentinel node biopsy in endometrial cancer — a feasibility study using cervical injection of radiotracer and blue dye

“…In order to avoid lymphadenectomy, the sentinel lymph node (SLN) concept has been applied to the treatment of several solid tumors [7][8][9]. This concept has also been used in endometrial cancer patients since 1996 and many groups reported their experience on this technique thus far [10,11].…”