Acerca de los ensayos clínicos en el ámbito quirúrgico. Reflexiones, dificultades y desafíos

A, Carlos Manterola; N, Viviana Pineda; G, Manuel Vial; C, Antonio Sanhueza

doi:10.4067/s0718-40262009000500017

Cited by 5 publications

(3 citation statements)

References 27 publications

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“…The study designs that involve a follow-up time are cohort studies (among the observational studies) and the RCT (among the experimental studies), both with all their respective variants Manterola et al, 2009). Nevertheless, it has been verified that between 70 % and 80 % of articles on therapy or TP are reports and prospective and retrospective case series (Manterola et al, 2006a;Manterola et al, 2006b;Manterola & Grande, 2010).…”

Section: Types Of Design and Their Level Of Evidencementioning

confidence: 99%

How to Evaluate and Interpret a Scientific Article About Therapy Or Therapeutic Procedures?

2017

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SUMMARY:Regardless of the subject area and design used, it has been verified that between 40% and 60% of the studies published in biomedical journals are articles about therapy or therapeutic procedures (TP). Anyone writing a manuscript related to therapy or TP or reading an article of this type must demand at the very least a clear, precise and concise objective with respect to the research conducted, explicit mention of the design used with the respective inherent methodological details, and the mention and execution of statistical tools and the measures of association, or at least the numbers needed to calculate these values. The aim of this manuscript is to present a synthesis of the fundamental elements for the correct writing, reading and assessment of such articles, regardless of the disciplinary area in which the research originated.

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Section: Types Of Design and Their Level Of Evidencementioning

confidence: 99%

How to Evaluate and Interpret a Scientific Article About Therapy Or Therapeutic Procedures?

2017

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“…Además, no se dispone de resultados por un largo tiempo 2,5 . Otros diseños de que permiten estudiar de forma adecuada el pronóstico, los FR y los FP son los ensayos clínicos [3][4][5][6] ; y, se ha verificado además, que un importante número de artículos sobre pronóstico corresponden a estudios de casos y controles, y series de casos prospectivas y retrospectivas [7][8][9][10] . En los escenarios de pronóstico, suele existir asociado a ellos los términos asociación y causalidad; o relación Causa y Efecto; de tal forma que el objetivo principal de un estudio sobre pronóstico es determinar causalidad o asociación, en la relación agente etiológico-EI.…”

Section: Tipos De Diseño Y Su Nivel De Evidenciaunclassified

Cómo valorar e interpretar un artículo sobre pronóstico

D¹,

A²,

Otzen³

2013

Rev Chil Cir

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How to assess and interpret a prognostic studyPrognosis is the prediction of the evolution of a given disease or event of interest and the frequency of occurrence of specific outcomes. The ideal study design to assess prognosis are cohort studies. However many prognostic studies have case-control or case series designs. Prognostic studies should include all participants with the event of interest of a determinate geographical region, to avoid bias. The measurement precision and exactitude of intervening variables and outcomes, the identification of confounding variables and an adequate follow up period, have a great influence on the methodological quality of prognostic studies. Prognosis is usually expressed as survival, disease free or remission free rates. This article provides basic methodological concepts that should be considered when evaluating a prognostic study.Key words: Prognostic, cohort studies, rates. ResumenPronóstico es una predicción de la evolución de una enfermedad o evento de interés (EI), que se asocia a posibles resultados del EI y a la frecuencia con la cual se puede esperar que se produzcan. El diseño ideal para estudiar pronóstico son los estudios de cohortes, no obstante lo cual, se ha verificado que un importante número de artículos sobre pronóstico corresponden a estudios de casos y controles, y series de casos. Los estudios sobre pronóstico se deben realizar con una población integrada por todas las personas con el EI de una región geográfica definida; es decir, deben basarse en una descripción completa de los individuos estudiados para asegurar una muestra reducida de sesgos. La calidad metodológica de un estudio sobre pronóstico es influenciada por la precisión y exactitud con la que se definen y miden las variables de exposición y resultado; así como por la prolijidad con la que se identifican las potenciales variables de confusión. Involucran un Rev.

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“…Los diseños de estudio que involucran un tiempo de seguimiento son los estudios de cohortes (entre los estudios de tipo observacional) y los EC (entre los estudios experimentales); ambos con todas sus respectivas variantes [23][24][25][26] . No obstante ello, se ha verifi cado que entre el 70% y 80% de los artículos sobre tratamiento o PT corresponden a reporte y series de casos, prospectivas y retrospectivas [3][4][5]27 .…”

Section: Tipos De Diseño Y Su Nivel De Evidenciaunclassified

Cómo valorar e interpretar un artículo sobre tratamiento o procedimientos terapéuticos

2010

Rev Chil Cir

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How to evaluate and interpret an article about therapy or therapeutic procedures Independent of the thematic area and design employed, it was verifi ed that between 40% and 60% of published studies in surgical scientifi c journals are related with treatment or therapeutic procedures (TP). The aim of this manuscript is to present a synthesis of the key elements for proper writing, reading and assessment of articles related with treatment or TP, regardless of disciplinary area which has arisen in the investigation. Who writes a manuscript relating to treatment or PT, or who read an article of this type should require at least a clear, accurate and concise objective, on the stage of the research being conducted, the explicit mention of the design used with the respective methodological details inherent in this, and the endorsement and implementation of statistical tools and measures of association, or at least the numbers needed to calculate these values.

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Acerca de los ensayos clínicos en el ámbito quirúrgico. Reflexiones, dificultades y desafíos

Cited by 5 publications

References 27 publications

How to Evaluate and Interpret a Scientific Article About Therapy Or Therapeutic Procedures?

How to Evaluate and Interpret a Scientific Article About Therapy Or Therapeutic Procedures?

Cómo valorar e interpretar un artículo sobre pronóstico

Cómo valorar e interpretar un artículo sobre tratamiento o procedimientos terapéuticos

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