Acetals of lactams and amides. 42. Reactions of enamino amides and enamino esters with some formylating agents. Synthesis of derivatives of 2-pyridone and of pyrimidin-4- and -6-ones

Reactions of diethyl 2-(ethoxymethylene)malonate with 2-cyanoacetanilides: unexpected transfer of the ethoxymethylene moiety

“…15 A mixture of 0.02 mol of the appropriate CH-acid 1a-c and triethylorthoformiate (0.04 mol) was refluxed in 0.06 mL of acetic anhydride. Then volatile waste-products were slowly distilled off at atmosphere pressure until temperature reached 82 ºC.…”