Acetone Sensor Based on FAIMS-MEMS

Zhang, Junna; Cheng, Liang; Liang, Ting; Liu, Ruifang; Zhao, Zhujie; Qi, Lei; Ghaffar, Abdul; Xiong, Jijun

doi:10.3390/mi12121531

Cited by 4 publications

(5 citation statements)

References 34 publications

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“…The better the square wave shape, the better the separation performance of the FAIMS. We used the square wave generated by the flyback structure, which can more effectively improve the separation effect of FAIMS [ 31 , 32 , 33 , 34 , 35 , 36 , 37 ].…”

Section: Sensor Principle and Sensor Designmentioning

confidence: 99%

Multi-Channel MEMS-FAIMS Gas Sensor for VOCs Detection

et al. 2023

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Aimed at the problems of a large equipment size, long time and high price of environmental VOC gas detection, the FAIMS-VOC gas sensor was designed and prepared according to the principle that the ionization energy of the common VOC gas is less than 10.6 eV. The sensor is small in size, fast in detection, low in power consumption, and can work continuously. The sensor was fabricated through the MEMS process, a specific process which included photolithography, etching, anodic bonding, etc. The sensor is 5160 μm long, 5300 μm wide and 800 μm high. We built a test system to detect two typical VOC gases: isobutylene and acetone. The results show that in the detection of isobutylene gas and acetone gas, the sensor voltage value changes with the change of gas concentration. The linearity of testing isobutylene is 0.961, and the linearity of testing acetone is 0.987. When the isobutylene gas concentration is 50 ppm, the response time is 8 s and the recovery time is 6 s; when the acetone gas concentration is 50 ppm, the response time is 9 s and the recovery time is 10 s. In addition, the sensor demonstrates good repeatability and stability, which are conducive to the detection of VOCs in the environment.

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Section: Sensor Principle and Sensor Designmentioning

confidence: 99%

Multi-Channel MEMS-FAIMS Gas Sensor for VOCs Detection

et al. 2023

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“…However, only BIOSENSE, LEVL and Ketonix have received the FDA-approval for diet management and diabetes diagnosis [72]. In the context of diabetes care, however, exhaled breath analysis is currently mainly investigated regarding diabetes diagnosis and not as a CGM sensing system [73][74][75].…”

Section: Exhaled Breath Analysismentioning

confidence: 99%

“…Especially, sensing using exhaled breath is regarded as controversial in the discussion regarding the correlation between BGL and measured acetone because of the significant influence of various factors. In consequence, exhaled breath is currently commercially investigated for diet management or diabetes diagnosis and not as a CGM sensing system [73][74][75]. However, for example GLUCAIR™ is currently working on a commercial solution for non-invasive blood glucose monitoring using exhaled breath [43].…”

Section: Non-invasive Sensor Principlesmentioning

confidence: 99%

Commercial and Scientific Solutions for Blood Glucose Monitoring—A Review

Xue

Thalmayer

Zeising

et al. 2022

Sensors

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Diabetes is a chronic and, according to the state of the art, an incurable disease. Therefore, to treat diabetes, regular blood glucose monitoring is crucial since it is mandatory to mitigate the risk and incidence of hyperglycemia and hypoglycemia. Nowadays, it is common to use blood glucose meters or continuous glucose monitoring via stinging the skin, which is classified as invasive monitoring. In recent decades, non-invasive monitoring has been regarded as a dominant research field. In this paper, electrochemical and electromagnetic non-invasive blood glucose monitoring approaches will be discussed. Thereby, scientific sensor systems are compared to commercial devices by validating the sensor principle and investigating their performance utilizing the Clarke error grid. Additionally, the opportunities to enhance the overall accuracy and stability of non-invasive glucose sensing and even predict blood glucose development to avoid hyperglycemia and hypoglycemia using post-processing and sensor fusion are presented. Overall, the scientific approaches show a comparable accuracy in the Clarke error grid to that of the commercial ones. However, they are in different stages of development and, therefore, need improvement regarding parameter optimization, temperature dependency, or testing with blood under real conditions. Moreover, the size of scientific sensing solutions must be further reduced for a wearable monitoring system.

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“…2,3 Currently, FAIMS mainly includes cylindrical and plate structures. [4][5][6] Cylindrical FAIMS is effective in ion focusing 4 and obtaining high signal strengths, so it has been widely used in commercial FAIMS applications. However, some scholars have pointed out that the signal-resolving power can be significantly improved by reducing the curvature of the FAIMS electrode.…”

Section: Introductionmentioning

confidence: 99%

“…Currently, FAIMS mainly includes cylindrical and plate structures 4‐6 . Cylindrical FAIMS is effective in ion focusing 4 and obtaining high signal strengths, so it has been widely used in commercial FAIMS applications.…”

Section: Introductionmentioning

confidence: 99%

Design and experiment of high‐field asymmetric waveform ion mobility spectrometry chip based on an integrated temperature control printed circuit board structure

Zeng,

Zhang,

Wang

et al. 2024

Rapid Comm Mass Spectrometry

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RationaleDuring the detection of volatile organic compounds (VOC) using high‐field asymmetric waveform ion mobility spectrometry (FAIMS), the ambient temperature significantly impacts the accuracy of planar FAIMS. To mitigate the influence of ambient temperature on detection accuracy and enhance resolution, a FAIMS system based on the inner impedance characteristics of a printed circuit board (PCB) was designed for temperature control.MethodsThis study, conducted under standard atmospheric pressure, aimed to assess the signal stability of a planar FAIMS instrument with and without temperature control, and the effect of temperature change on the detection ability of acetone, ethanol, and their mixture was studied using PCB self‐heating.ResultsExperimental results demonstrated that the base noise in FAIMS with temperature control was 0.2 pA, whereas that in FAIMS without temperature control was 1.8 pA. Notably, with increasing temperature, the detection ability of FAIMS changes accordingly. The optimal relative detection ability of acetone was observed when the electrode plate was heated to 45°C under an electric field of 15 kV/cm.ConclusionsThis study provides a novel approach to improve the resolving power of FAIMS systems and their signal‐to‐noise ratio. The utilization of a PCB‐based temperature control proved effective in stabilizing FAIMS signal characteristics and optimizing detection capabilities, particularly for VOCs such as acetone. These findings have significant implications for improving the accuracy and resolving power of FAIMS systems in VOC detection applications.

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Acetone Sensor Based on FAIMS-MEMS

Cited by 4 publications

References 34 publications

Multi-Channel MEMS-FAIMS Gas Sensor for VOCs Detection

Multi-Channel MEMS-FAIMS Gas Sensor for VOCs Detection

Commercial and Scientific Solutions for Blood Glucose Monitoring—A Review

Design and experiment of high‐field asymmetric waveform ion mobility spectrometry chip based on an integrated temperature control printed circuit board structure

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