Achillea ligustica: composition and antimicrobial activity of essential oils from the leaves, flowers and some pure constituents

Abstract

Abstract:The composition of the essential oils obtained from the leaves and the flowers of Achillea ligustica (Asteraceae) growing in Sicily has been studied. The main constituents of the leaves were 4-terpineol (19.3%), carvone (8.9%), γ-terpinene (7.2%) and β-phellandrene (6.8%). 4-terpineol (12.0%), carvone (10.0%), and β-phellandrene (5.4%), along with linalool (20.4%) and cedrol (4.3%) were detected in the flower's oil. Furthermore, the antimicrobial activity of the essential oils and of some of the main constituents were assayed on bacteria and fungi.

Chemical composition of the essential oils and extracts of Achillea species and their biological activities: A review

“…In addition, sap of A. ligustica All. is traditionally prescribed as a proper anthelmintic agent in Sicily (Bruni et al, 1997;Viegi et al, 2003;Bader et al, 2007).…”

“…fumigatus (Bezic et al, 2003;Bekhechi et al, 2011;Falconieri et al, 2011), A. niger (Bezic et al, 2003;Ristic et al, 2004;Stojanovic et al, 2005;Falconieri et al, 2011), C. albicans (Barel et al, 1991;Magiatis et al, 2002;Unlu et al, 2002;Bezic et al, 2003;Candan et al, 2003;Sokmen et al, 2003;El-Shazly et al, 2004;Sokmen et al, 2004;Stojanovic et al, 2005;Tuberoso et al, 2005;Iscan et al, 2006;Bader et al, 2007;Karamenderes et al, 2007;Maggi et al, 2009;Turkoglu et al, 2010;Falconieri et al, 2011;Kucukbay et al, 2011;Radulovic et al, 2012;Albayrak, 2013;Kazemi and Rostami, 2015;Turkmenoglu et al, 2015;Fahed et al, 2016), C. glabrata (Magiatis et al, 2002;Al-Snafi, 2013), C. krusei (Candan et al, 2003;Sokmen et al, 2003;Falconieri et al, 2011;Turkmenoglu et al, 2015), C. herbarum (Bekhechi et al, 2011), C. kefyr (Ghasemi et al, 2008), C. krusei (Candan et al, 2003;Sokmen et al, 2003;Falconieri et al, 2011;Turkmeno...…”

“…As an antimicrobial and haemostatic, to treat stomachache c , Inf d : To relief gastralgia and neuralgia as well as a cataplasm against rheumatism and skin disorders; Sap: An anthelmintic agent Italy (Bruni et al, 1997;Viegi et al, 2003;Bader et al, 2007) A. ligustica All.…”

Antimicrobial Efficacy of Achillea ligusticaAll. (Asteraceae) Essential Oils against Reference and Isolated Oral Microorganisms

“…This can be due to the use of fresh material instead of dry one. In literature, the following values were reported: 0.4 and 0.13 -0.90% for population from Corsica [17] [18], respectively, 0.43 -0.88% for population from Sardinia [19], and 0.38 -0.48% for population from Sicily [20].…”

Kazakh Ziziphora Species as Sources of Bioactive Substances

“…clinopodioides (0.36%-18.2%) [15,184] Sedative and anaesthetic (on silver catfish juveniles) [339]; depressant effect on the CNS and significant anticonvulsant activity probably due to interaction with GABA receptors [340,341] Low inhibition of acetylcholinesterase and butyrylcholinesterase [224] Relaxant effect on vascular smooth muscle [342] Review on some effects on cardiovascular system [221] Anticancer (melanoma) [343]; antiproliferative activity in two murine cancer cell lines through induction of necrosis and cell cycle arrest [344]; induction of apoptosis in human non-small cell lung cancer [345]; anti-tumoral activity in human melanoma cells by induction of caspase-dependent form of apoptosis [346] Antiviral activity against influenza A⁄PR⁄8 virus subtype H1N1 [231] Anti-inflammatory (inhibition of NO production in LPS-stimulated RAW-264.7 macrophages) [223]; anti-inflammatory [216]; anti-inflammatory activity in a murine model of oral candidiasis [347]; suppression of the production of TNFα, IL-1β, IL-8, IL-10 and PGE 2 by LPS-activated monocytes [348] Antibacterial against MRSA and CoNS [349] Low antinematocidal activity [281] Antimycotic (C. albicans) [307,350] Insecticidal (against L. serricorne) [351] Trypanocidal activity against Trypanosoma evansi [222] Molecules 2016, 21, 826 21 of 53…”