Achilles Tendinopathies

Ishikawa, Susan N.; Donley, Brian G.; Richardson, David R.; Murphy, G. Andrew

doi:10.1007/978-3-642-36801-1_181-1

Cited by 2 publications

(1 citation statement)

References 64 publications

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“…Achilles and patellar tendon are the most commonly affected in lower extremities, while rotator cuff and tennis elbow (extensor carpi radialis brevis) tendons are the ones affected in upper extremities [4,5]. Achilles tendon rupture is an example of acute injury, while Achilles tendinopathy is an example of the chronic overuse and is a common cause of disability in recreational and professional athletes [6]. In the last few decades, tendon injury occurrence has increased, and it is reported to be between 30 and 50% of sport-related injuries and is mostly traced back to exercise-related overuse [7].…”

Section: Introductionmentioning

confidence: 99%

Association of the matrix metalloproteinase 3 (MMP3) single nucleotide polymorphisms with tendinopathies: case-control study in high-level athletes

Briški

Vrgoč

Knjaz

et al. 2020

International Orthopaedics (SICOT)

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Background Matrix metalloproteinases (MMPs) play an important role in matrix remodelling, as well as in tendon integrity. Due to overuse, athletes often develop chronic tendinopathies. If not treated, they lead to severe impairment, even complete tendon ruptures. Aim The main purpose of this study was to investigate whether three functional polymorphisms within the MMP3 gene are associated with increased risk of developing tendinopathies in high-level Croatian athletes. Methods We have recruited one hundred fifty-five (63 high-level athletes with diagnosed tendinopathies and 92 asymptomatic controls) unrelated Caucasians for this case-control genetic study. All participants were genotyped for three single nucleotide polymorphisms (SNP) within the MMP3 gene: rs591058 C/T, rs650108 A/G and rs679620 G/A using the pyrosequencing method.Results The MMP3 rs650108 GG (P = 0.0074) and rs679620 AA (P = 0.0119) genotypes were significantly over-represented in cases compared with controls, while rs591058 TT (P = 0.0759), as well as haplotype variant T -G -A (P = 0.06), implicated that there is an indication of predisposition for tendinopathies. Conclusion These results support association between functional variants within the MMP3 gene and the risk of tendinopathies in high-level athletes. Further research is needed to replicate these results in a larger population.

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Section: Introductionmentioning

confidence: 99%

Association of the matrix metalloproteinase 3 (MMP3) single nucleotide polymorphisms with tendinopathies: case-control study in high-level athletes

Briški

Vrgoč

Knjaz

et al. 2020

International Orthopaedics (SICOT)

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Injury and Illness in Elite Athletics: A Prospective Cohort Study Over Three Seasons

Kelly¹,

Pollock

Polglass

et al. 2022

International Journal of Sports Physical Therapy

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Background Athletics (also known as track and field) is one of the most popular sports in the world and is the centrepiece of the Summer Olympic Games. Participation in athletics training and competition involves a risk of illness and injury. Purpose To describe injury and illness in British Olympic track and field athletes over three full training and competition seasons. Study Design Descriptive Epidemiology Study Methods A total of 111 athletes on the British national program were followed prospectively for three consecutive seasons between 2015-2018. Team medical personnel recorded all injuries and illnesses during this time, following current consensus-based methods. All data pertaining to these records were reviewed and analyzed for sports injury and illness epidemiological descriptive statistics. Results The average age of the athletes was 24 years for both males and females (24 years, +/- 4). Total exposure for the three seasons was 79 205 athlete days (217 athlete years). Overuse injuries (56.4%) were more frequent than acute injuries (43.6%). The thigh was the most common injury location (0.6 per athlete year), followed by the lower leg (0.4 per athlete year) and foot (0.3 per athlete year). Muscle and tendon were the most commonly injured tissues, while strains and tears were the most common pathology type. Hamstring muscle strain was the most common diagnosis causing time loss, followed by Achilles tendinopathy and soleus muscle strain. Respiratory illness was the most common illness type (0.3 per athlete year). Conclusion Hamstring strains, Achilles tendinopathy, and soleus strains are the most common injuries in athletics and have highest burden. Respiratory illness is the most common illness and has the highest burden. Knowledge of this injury and illness profile within athletics could be utilised for the development of targeted prevention measures within the sport at the elite level. Level of Evidence 3

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Achilles Tendinopathies

Cited by 2 publications

References 64 publications

Association of the matrix metalloproteinase 3 (MMP3) single nucleotide polymorphisms with tendinopathies: case-control study in high-level athletes

Association of the matrix metalloproteinase 3 (MMP3) single nucleotide polymorphisms with tendinopathies: case-control study in high-level athletes

Injury and Illness in Elite Athletics: A Prospective Cohort Study Over Three Seasons

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