Acneiform lesions in Becker's nevus and breast hypoplasia

Abstract

An 18‐year‐old woman was referred for the evaluation of a dull gray macule on the left breast. From the age of 13 years, the patient noted breast asymmetry beginning with the development of the left breast and the presence of a pigmented stain on its border. Physical exploration revealed hypoplasia of the left breast and a homogeneous, light brown macule on the side of the breast (Fig. 1) without infiltration. Papules and pustules were located mainly around the Becker's nevus on the left anterior chest wall. Biopsy specimens with Fontana's stain disclosed a hyperpigmented acanthotic epidermis. A diagnosis of Becker's nevus, acne, and hypoplasia of the breast was made. 1 Hypoplasia of the left breast and a homogeneous light brown macule with acneiform lesions

Síndrome do nevo de Becker

“…As an androgen-dependent disorder, it is much more common in males (5:1) and in adolescence. 1,4 In the epidermis, histopathology shows acanthosis and hyperpigmentation of the basal layer and in the dermis there is hyperplasia of the arrector pili muscle with melanophages, as seen in this patient. 1,2,4 Despite the hyperchromia, Becker's nevus does not belong to the group of melanocytic lesions.…”

“…1,4 In the epidermis, histopathology shows acanthosis and hyperpigmentation of the basal layer and in the dermis there is hyperplasia of the arrector pili muscle with melanophages, as seen in this patient. 1,2,4 Despite the hyperchromia, Becker's nevus does not belong to the group of melanocytic lesions. It is considered a particular form of epidermal nevi similar to verrucous epidermal nevus, sebaceous nevus of Jadassohn, nevus comedonicus, eccrine nevus, apocrine nevus and white sponge nevus, which are named in accordance with the preponderant structure (Table 1).…”

“…1 Becker nevus syndrome is also an androgendependent disorder as is Becker's nevus and is therefore more commonly found in adolescence due to the increased hyperpigmentation of the nevus and the hair. [1][2][3][4][5] The proportion of women sufferers is the same as that of men, although it is more easily diagnosed in women due to the more visible breast hypoplasia. 1,2 Many of the findings associated with this syndrome are believed to be the result of the increase in the number of androgen receptors in certain areas.…”

Becker Nevus on the Face: A Rare Presentation: Case Report

“…İpsilateral pektoralis majör kası hipo/aplazisi, politelia (aksesuar meme başı), konjenital adrenal hiperplazi, kistik lenfanjiyom, akneiform lezyonlar, epidermal nevüs, konektif doku nevüsü, Bowen hastalığı, malign melanom, liken planus, skolyoz ve lokalize lipoatrofi bildirilen diğer anomalilerdir. 13,14 BN'nin ayırıcı tanısında, "cafe-au-lait" lekesi, konjenital melanositik nevüs, pleksiform nörofibrom ve konjenital düz kas hamartomu bulunmaktadır.…”

Segmental Acne versus Mosaic Conditions with Acne Lesions

“…We identified 10 cases of acne lesions confined to a Becker nevus (8 males, 2 females; 8 whites, 2 Indians; average age 19.4 years, average duration of the rash 3.7 years) and were therefore arranged in a segmental, block-like pattern [13,14,15,16,17,18,19,20]. Nine nevi involved the chest, one the arm; 5 were on the left side, 4 on the right side, 1 unknown.…”