Acoustic platforms meet MXenes – a new paradigm shift in the palette of biomedical applications

Richard, Bartholomew; Shahana, C.; Vivek, Raju; M., Amarendar Reddy; Rasheed, P. Abdul

doi:10.1039/d3nr04901a

Cited by 5 publications

(2 citation statements)

References 137 publications

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“…MXene is 2D transition metal carbides or carbonitrides with the composition M n+1 X n T x , where M is a transition metal; X is carbon or nitrogen; T represents surface functional groups such as -OH, =O, and -F; and n is an integer from one to four [ 85 , 102 , 103 , 104 , 105 ]. In particular, the abundant surface functional groups on MXene enable strong adhesion to various substrates.…”

Section: Sound Emittermentioning

confidence: 99%

Intelligent, Flexible Artificial Throats with Sound Emitting, Detecting, and Recognizing Abilities

Fu,

Deng,

Liu

et al. 2024

Sensors

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In recent years, there has been a notable rise in the number of patients afflicted with laryngeal diseases, including cancer, trauma, and other ailments leading to voice loss. Currently, the market is witnessing a pressing demand for medical and healthcare products designed to assist individuals with voice defects, prompting the invention of the artificial throat (AT). This user-friendly device eliminates the need for complex procedures like phonation reconstruction surgery. Therefore, in this review, we will initially give a careful introduction to the intelligent AT, which can act not only as a sound sensor but also as a thin-film sound emitter. Then, the sensing principle to detect sound will be discussed carefully, including capacitive, piezoelectric, electromagnetic, and piezoresistive components employed in the realm of sound sensing. Following this, the development of thermoacoustic theory and different materials made of sound emitters will also be analyzed. After that, various algorithms utilized by the intelligent AT for speech pattern recognition will be reviewed, including some classical algorithms and neural network algorithms. Finally, the outlook, challenge, and conclusion of the intelligent AT will be stated. The intelligent AT presents clear advantages for patients with voice impairments, demonstrating significant social values.

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Section: Sound Emittermentioning

confidence: 99%

Intelligent, Flexible Artificial Throats with Sound Emitting, Detecting, and Recognizing Abilities

Fu,

Deng,

Liu

et al. 2024

Sensors

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“…MXene, one of the youngest members in the 2D materials family, possesses unique features such as exceptional electrical conductivity and hydrophilicity, making them extremely promising candidates for a wide range of applications like energy storage, environmental remediation, and diagnostic applications. , It was established that MXene can be used to make the composites with MOF to enhance their electrocatalytic activities toward electrochemical sensing applications. The recently reported literatures show many MOF–MXene composites that have shown excellent conductivity and are explored in various electrochemical applications .…”

Section: Introductionmentioning

confidence: 99%

Biological Metal–Organic Framework-Embedded MXene Nanocomposite as a Wearable Transducer Patch for Real-Time Monitoring of the Sleep Hormone

Richard,

Niyas,

Ankitha

et al. 2024

ACS Appl. Nano Mater.

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Sleep is an inherent property of human beings, and it is mainly associated with the sleep hormone melatonin (MEL). Abnormal levels of MEL can lead to disorders like hypertension, stress, dementia, Alzheimer's disease, etc. Therefore, continuous monitoring of this hormone is of great concern. In this study, we have developed a sensing platform by combining Nb 2 CT x MXene nanosheets with a zinc-based metal−organic framework (Zn-MOF). The MOF was synthesized using a zinc ion as the metal part and L-glutamic acid as the organic linker. Because the linker itself is a biological molecule, the synthesized MOF can be denoted as bio-MOF as a whole. This novel composite (Zn-MOF-Nb 2 CT x MXene) offers enhanced electrocatalytic properties, improved electrical conductivity, and increased active sites, making it wellsuitable for the electrochemical detection of MEL. Notably, the inlay of MOF nanoflakes onto the MXene nanosheets created a synergistic effect that greatly enhanced the electrochemical performance for MEL detection. The sensor made of a Zn-MOF-Nb 2 CT x MXene nanocomposite coated on carbon yarn (CY) exhibited a wide linear detection range for MEL, spanning from 1 to 100 μM, with a detection limit of 215 nM. Importantly, it displayed high selectivity against interfering compounds commonly encountered in body fluids. Also, to check the practical applicability of the sensor, we tried the detection of MEL in biological fluids like sweat, blood serum, and cerebrospinal fluid (CSF) to prove its practicability in real-time medical scenarios. Notably, the use of CY as the electrode material opens the door for its potential integration into a band-aid to make a wearable and point-of-care device for current health sector applications.

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Fabrication Methods, Structural, Surface Morphology and Biomedical Applications of MXene: A Review

Avinashi,

Mishra,

Singh

et al. 2024

ACS Appl. Mater. Interfaces

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Recently, two-dimensional (2-D) layered materials have revealed outstanding properties and play a crucial role for numerous advanced applications. The emerging transition metal carbides and nitrides, known as MXene with empirical formula M n+1 X n T x , have generated widespread attention and demonstrated impressive potential in various fields. The fabrication of 2-D novel MXene and its composites and their characterizations are applicable to vast applications in different areas such as energy storage, gas sensors, catalysis, and biomedical applications. In this review, the main focus is on the various synthesis methods, their properties, and biomedical applications. This review provides detailed illustrations of MXenes for many biomedical applications, including bioimaging, drug delivery, therapies, biosensors, tissue engineering, and antibacterial reagents. The challenges and future prospects were highlighted in a comprehensive manner, and the existing problems and potential for MXene-based biomaterials were analyzed with the goal of accelerating their use in the biomedical field.

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Acoustic platforms meet MXenes – a new paradigm shift in the palette of biomedical applications

Abstract: Acoustic applications of MXenes including artificial eardrum, photoacoustic imaging, acoustic sensors, sonodynamic therapy and thermoacoustic devices.

Cited by 5 publications

References 137 publications

Intelligent, Flexible Artificial Throats with Sound Emitting, Detecting, and Recognizing Abilities

Intelligent, Flexible Artificial Throats with Sound Emitting, Detecting, and Recognizing Abilities

Biological Metal–Organic Framework-Embedded MXene Nanocomposite as a Wearable Transducer Patch for Real-Time Monitoring of the Sleep Hormone

Fabrication Methods, Structural, Surface Morphology and Biomedical Applications of MXene: A Review

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