2024
DOI: 10.1021/acs.iecr.4c00518
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Acoustic Streaming to Control the Nucleation Kinetics of Paracetamol in a Tubular Microcrystallizer

Cedric Devos,
Aaron Doyle,
Michiel Van Eersel
et al.

Abstract: While tubular microcrystallizers offer distinct advantages over conventional crystallization setups for manipulating crystallization conditions, precisely controlling mixing, fluid shear, and therefore also the nucleation step remains a challenge.In this study, the potential of acoustic streaming as a tool to manipulate nucleation was investigated. Acoustic streaming is fluid flow as a result of the attenuation of an ultrasonic wave propagating through a viscous medium, which in the developed setup leads to th… Show more

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