Acquired ichthyosis as a presenting finding of Hodgkin’s lymphoma

Akpınar, Timur Selçuk; Özkök, Abdullah; Bakkaloğlu, Oğuz Kağan; Saka, Bülent

doi:10.1007/s12185-012-1173-z

Cited by 12 publications

(9 citation statements)

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“…However, malignancy accounts for half of the reported cases [2], most commonly Hodgkin's disease, representing about 70% of the cases [1, 7, 12, 13, 14, 15]. …”

Section: Discussionmentioning

confidence: 99%

“…Apart from neoplastic disorders, AI has been associated with a variety of diseases including infections, autoimmune/inflammatory and endocrine/metabolic diseases as well as nutritional conditions, medications and others (table 1 ) [ 1 , 2 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ]. However, malignancy accounts for half of the reported cases [ 2 ], most commonly Hodgkin's disease, representing about 70% of the cases [ 1 , 7 , 12 , 13 , 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

“…Cooper et al [ 16 ] suggested impaired epidermal lipogenesis as the mechanism of the cutaneous changes in AI. Transforming growth factor alpha, produced by tumor cells, has also been implicated in the pathogenesis of paraneoplastic AI [ 2 , 7 ]. Last, when associated with lymphoproliferative disorders, the deficiency is likely to be related to poor vitamin A absorption [ 1 , 12 , 13 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

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Acquired Ichthyosis Triggered by an Osseous Hemangiopericytoma: A Case Report and Review of the Literature

et al. 2014

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Ichthyoses are a heterogeneous group of cutaneous keratinization disorders that can be congenital or acquired. Apart from neoplastic disorders, the acquired form of ichthyosis (AI) has been associated with a variety of diseases including infections, autoimmune/inflammatory and endocrine/metabolic diseases as well as nutritional conditions, medications and others. However, malignancy accounts for half of the reported cases, most commonly including lymphoproliferative disorders. We present a case of AI as a paraneoplastic skin manifestation of a primary, osseous hemangiopericytoma (HP) accompanied by multiple liver metastases. We also review the literature and discuss the necessity of investigating underlying diseases, especially malignancy, when adult-onset ichthyosis arises.

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“…However, malignancy accounts for half of the reported cases [2], most commonly Hodgkin's disease, representing about 70% of the cases [1, 7, 12, 13, 14, 15]. …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Acquired Ichthyosis Triggered by an Osseous Hemangiopericytoma: A Case Report and Review of the Literature

et al. 2014

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“…La asociación más relevante dada su frecuencia e implicación pronóstica es el cáncer (1), sobre todo el Linfoma de Hodgkin . También hay casos asociados a micosis fungoide, linfoma anaplásico de células grandes, sarcoma de Kaposi, leiomiosarcoma y carcinomas de mama, ovario, cervix, hígado y pulmón entre otros (3,4). La ictiosis paraneoplásica generalmente cursa de forma paralela a la enfermedad causal (3,4,5) si bien en algunos casos puede preceder o ser posterior al diagnóstico de la misma (1,2).…”

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“…También hay casos asociados a micosis fungoide, linfoma anaplásico de células grandes, sarcoma de Kaposi, leiomiosarcoma y carcinomas de mama, ovario, cervix, hígado y pulmón entre otros (3,4). La ictiosis paraneoplásica generalmente cursa de forma paralela a la enfermedad causal (3,4,5) si bien en algunos casos puede preceder o ser posterior al diagnóstico de la misma (1,2). Actualmente no se conoce bien la etiopatogenia de este cuadro, aunque se ha postulado la producción de un factor de crecimiento por parte del tumor que induciría la proliferación del epitelio epidérmico susceptible (1).…”

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Acquired ichthyosis: a sign of malignancy

Arjona-Aguilera¹,

Blasco‐Morente²,

Pérez-López³

et al. 2015

Actual. Med.

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Inherited Disorders of Cornification

Oji

Metze

Traupe

2016

Rook's Textbook of Dermatology, Ninth Edition

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The majority of keratinization disorders are referred to as Mendelian disorders of cornification. This is a very broad group, clinically characterized by hyperkeratosis or visible scaling or both. This chapter deals with the ichthyoses, palmoplantar keratodermas (PPKs) and miscellaneous cornification disorders such as porokeratoses. It is aimed primarily at dermatologists and physician scientists who have to make a clinical diagnosis and provide adequate management for their patients. Therefore a nosology and classification scheme has been chosen that is based on clinicogenetic and morphological features. Clinical diagnoses are then discussed with their molecular pathology. Part of the chapter addresses the management of congenital ichthyoses. Various tables provide an overview on clinical and/or pathophysiologically related groups of diseases. Finally, several cornification disorders are discussed that do not have a genetic basis, but are acquired or are of unknown aetiology (e.g. acquired ichthyoses/PPKs or perforating keratotic disorders).

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Acquired ichthyosis as a presenting finding of Hodgkin’s lymphoma

Cited by 12 publications

References 1 publication

Acquired Ichthyosis Triggered by an Osseous Hemangiopericytoma: A Case Report and Review of the Literature

Acquired Ichthyosis Triggered by an Osseous Hemangiopericytoma: A Case Report and Review of the Literature

Acquired ichthyosis: a sign of malignancy

Inherited Disorders of Cornification

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