Acquired progressive lymphangioma

Benign Lymphangioendothelioma

“…Нами были проанализированы 42 случая доброка-чественной лимфангиоэндотелиомы, опубликованные в печати [2][3][4][5][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. Среди пациентов преобладали лица мужского пола (мужчин было 25 (59,5 %), женщин -17 (40,5 %)).…”

“…Возможно, имеют значения гормональные нарушения, так как в одном слу-чае отмечался быстрый рост образования в период по-лового созревания [8]. Наконец, на основании иммуноги-стохимических исследований высказано предположение о том, что ДЛ представляет сосудистую гамартому с тре-мя компонентами в виде лимфатических сосудов, крове-носных сосудов и гладких мышц [10,15].…”

Benign Lymphangioendothelioma - A Case Report

“…The cells are also variably positive for factor VIII, Ulex europaeus agglutinin I, CD31, and CD34 [2-4]. However, Tadaki et al, reported negative results for all these markers [5]. Benign lymphangioendothelioma should be histopathologically distinguished from Kaposi's sarcoma, especially in patch …”

“…It is postulated that benign lymphangioendothelioma may be a response to different inflammatory stimuli rather than a true neoplasm, because it has been described after different traumas, including surgery, radiation therapy, femoral arteriography, hip inflammation and tick bites [2][3][4]. Another pathogenic explanation could be a hormonal stimulus, because rapidly enlarging lesions have been described in many pubescent and prepubescent patients [5]. Finally, another hypothesis that has been suggested is that benign lymphangioendothelioma represents a complex vascular hamartoma with three components such as lymphatic vessels, blood vessels and smooth muscle [6].…”

“…Men and women are equally affected [1]. The neoplasm is located mainly on legs, head and neck, even though there also are examples described in the wrist, shoulder, arm, forearm, breast, back, abdominal wall, buttocks, toes, soles and oral mucosa [2][3][4][5][6]. No haematologic or lymphatic dissemination has been yet described.…”