Actinobacteria: Versatile Microorganisms with Medical and Pharmaceutical Application

Araujo-Melo, Rosilma de O.; Souza, Igor Felipe Andrade Costa de; Vicalvi-Costa, Maria C. V.; Araújo, Janete Magalí de; Sena, Kêsia X. R. F. de; Coelho, Luana Cassandra Breitenbach Barroso

doi:10.9734/bbj/2016/28728

Cited by 2 publications

(5 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The filamentous form is an intrinsic characteristic of the Streptomyces genus. The name of this group originated from this characteristic, with the Greek words aktis and mykes merged to refer to the bacteria with radial growth similar to fungi 1,2 . This taxon is primarily mesophilic, chemoorganotrophic, and saprophytic, with the exception of some species that grow at extreme pH levels, temperatures, and salt concentrations 3,4 …”

Section: Microbiology Of Actinomycetesmentioning

confidence: 99%

“…The name of this group originated from this characteristic, with the Greek words aktis and mykes merged to refer to the bacteria with radial growth similar to fungi. 1,2 This taxon is primarily mesophilic, chemoorganotrophic, and saprophytic, with the exception of some species that grow at extreme pH levels, temperatures, and salt concentrations. 3,4 The morphologic characteristics of actinomycetes can be observed macroscopically and microscopically.…”

Section: Morphologymentioning

confidence: 99%

See 1 more Smart Citation

Genus Streptomyces: Recent advances for biotechnological purposes

Júnior

Sousa²,

Oliveira

et al. 2023

Biotech and App Biochem

View full text Add to dashboard Cite

Actinomycetes are a distinct group of filamentous bacteria. The Streptomyces genus within this group has been extensively studied over the years, with substantial contributions to society and science. This genus is known for its antimicrobial production, as well as antitumor, biopesticide, and immunomodulatory properties. Therefore, the extraordinary plasticity of the Streptomyces genus has inspired new research techniques. The newest way of exploring Streptomyces has comprised the discovery of new natural metabolites and the application of emerging tools such as CRISPR technology in drug discovery. In this narrative review, we explore relevant published literature concerning the ongoing novelties of the Streptomyces genus.

show abstract

Section: Microbiology Of Actinomycetesmentioning

confidence: 99%

Section: Morphologymentioning

confidence: 99%

Genus Streptomyces: Recent advances for biotechnological purposes

Júnior

Sousa²,

Oliveira

et al. 2023

Biotech and App Biochem

View full text Add to dashboard Cite

show abstract

“…These bacteria are mainly aerobic and mesophilic, however, some of them are able to grow under extreme conditions of oxygen absence, pH, temperature, and salt concentration. The microscopic morphology of Actinobacteria colonies is similar to fungi, endowed of grouped thin hyphae to form a characteristic mycelium (Barka et al 2016, Araújo-Melo et al 2017. Macroscopically, Actinobacteria colonies may have various colors, dried aspect, crinkled appearance, and strong adherence to the surface when cultured on agar plates.…”

Section: Actinobacteriamentioning

confidence: 99%

“…Macroscopically, Actinobacteria colonies may have various colors, dried aspect, crinkled appearance, and strong adherence to the surface when cultured on agar plates. The taxonomy of this group was based on cell wall content but currently is also focused on 16S and 23S rRNA sequences and different genes (Nouioui et al 2018, Araújo-Melo et al 2017.…”

Section: Actinobacteriamentioning

confidence: 99%

“…The Actinobacteria have already been isolated from herbaceous, arboreal, ornamental, and medicinal plants being frequent the isolation of rare genus as Nocardia, Pseudonocardia, and Actinomadura (Tanvir et al 2016). The first Actinobacteria isolated from vegetal tissues were classified as belonging to the Frankia genus (Araújo-Melo et al 2017). The knowledge about endophytic Actinobacteria has increased, however, this niche is still considered untapped or misexplored.…”

Section: Plantsmentioning

confidence: 99%

See 1 more Smart Citation

Free Radicals and Actinobacteria as a Misexplored Goldmine of Antioxidant Compounds

Oliveira

Gusmão

Silva

et al. 2021

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

Free radicals are highly reactive unstable molecules, which can be synthesized in different ways, considered harmful and threatening to humans; these chemical species have free traffi c throughout the human body, interacting with biological molecules and human body organ tissues. The interaction between free radicals and biological molecules is the main factor for disease development or pre-existing disease symptoms aggravation. Antioxidants are chemical compounds able to donate electric charge to stabilize molecules such as free radicals. Recent studies have proved the benefi ts of antioxidants intake in health improvement. In this way, the search for natural sources of antioxidants has become an ascending trend. In this fi eld, the microbial sources are considered poorly explored compared to the numerous amount of other compounds obtained from them, especially from Actinobacteria. The searched literature about Actinobacteria highlights an important capacity of producing natural antioxidants; however, there is a lack of in vivo studies of these isolated compounds. In this review, we gathered information that supports our point of view that Actinobacteria is a truly renewable and superfi cially explored source of natural antioxidants. Furthermore, our purpose is also to point this limitation and stimulate more researches in this area.

show abstract

Actinobacteria: Versatile Microorganisms with Medical and Pharmaceutical Application

Cited by 2 publications

References 45 publications

Genus Streptomyces: Recent advances for biotechnological purposes

Genus Streptomyces: Recent advances for biotechnological purposes

Free Radicals and Actinobacteria as a Misexplored Goldmine of Antioxidant Compounds

Contact Info

Product

Resources

About