Action trypanocide du chlorhydrate de chlorure d'Isométamidium (+) sur &lt;em&gt;Trypanosoma evansi&lt;/em&gt; et essai de traitement de la trypanosomiase du dromadaire

Balis, John U.; Richard, Didier

doi:10.19182/remvt.8075

Cited by 10 publications

(1 citation statement)

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“…Isometamidium chloride can be used for cure of T. evansi infection in the camel but the drug has no prophylactic effects (7,60). Adverse effects of the drug include inhibition of cholines-s RESSOURCES ANIMALES synthèse terase (5).…”

Section: Neuroleptanalgesiamentioning

confidence: 99%

Synthèse sur les effets indésirables de certains médicaments chez le chameau

Dughayrn¹,

Afaleq²,

Homeida³

1998

Rev. Elev. Med. Vet. Pays Trop.

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Cette synthèse fait le point sur les données pharmacologiques de base concernant le métabolisme de médicaments, les réactions indésirables et autres effets toxiques secondaires provoqués chez le chameau par des agents anti-infectieux courants ainsi que des dépresseurs du système nerveux central et des antiprotozoaires. Certaines caractéristiques du chameau, telles qu'un taux de filtration glomérulaire relativement faible, un long néphron, un faible taux de renouvellement de l'eau, des hématies avec des formes particulières et une faible activité enzymatique du métabolisme des médicaments, peuvent modifier le comportement pharmacocinétique des médicaments chez cette espèce.

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Section: Neuroleptanalgesiamentioning

confidence: 99%

Synthèse sur les effets indésirables de certains médicaments chez le chameau

Dughayrn¹,

Afaleq²,

Homeida³

1998

Rev. Elev. Med. Vet. Pays Trop.

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A survey of some drugs commonly used in the camel

Ali

1988

Veterinary Research Communications

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Specific recommendations for drug dosages for the camel are rare and doses for this species are usually extrapolated from those recommended for other species. The pharmacology and toxicity of drugs likely to be used in the camel needs to be further studied to ensure the efficacy and safety of these drugs in this species. Most of the reported work is on the chemotherapeutic efficacy of a few drugs long in use in other species against trypanosomiasis, mange and gastrointestinal nematodes. Areas of study most deficient are pharmacodynamics, pharmacokinetics and drug metabolism. The anatomical, physiological and biochemical peculiarities of the camel warrant more pharmacological and toxicological studies in this species. This article surveys the literature on the pharmacology, toxicity and therapeutic uses of some antiparasitic and antibacterial drugs and central nervous system depressants commonly used in the camel. It appears that camels are more susceptible to the toxic action of some trypanocidal drugs than other species. In certain cases they may metabolize some drugs differently. In general, the camel appears to be a good subject for analgesics and anaesthetics.

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Trypanosomiasis due toTrypanosoma evansi (steel, 1885) balbiani, 1888. a review of recent research

Mahmoud

Gray

1980

Trop Anim Health Prod

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Action trypanocide du chlorhydrate de chlorure d'Isométamidium (+) sur <em>Trypanosoma evansi</em> et essai de traitement de la trypanosomiase du dromadaire

Cited by 10 publications

References 1 publication

Synthèse sur les effets indésirables de certains médicaments chez le chameau

Synthèse sur les effets indésirables de certains médicaments chez le chameau

A survey of some drugs commonly used in the camel

Trypanosomiasis due toTrypanosoma evansi (steel, 1885) balbiani, 1888. a review of recent research

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