Activated and Micronized Zeolite in the Modulation of Cellular Oxidative Stress in Mexican Smokers: A Randomized Clinical Trial

Atitlán-Gil, Alfonso; Loza, Martín Mauricio Bretón de la; Jiménez-Ortega, J. C.; Belefant-Miller, Helen; Betanzos‐Cabrera, Gabriel

doi:10.24875/ric.17002125

Cited by 5 publications

(4 citation statements)

References 22 publications

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“…Activated and micronized zeolites are used as detoxifying agents in humans. Detoxification is attributed to their ability to reduce lipid peroxidation by scavenging free radicals [ 13 ]. In the present study, the effect of supplemental zeolite on antioxidant status of turkey are shown in Table 6a and Table 6b .…”

Section: Resultsmentioning

confidence: 99%

“…Activated and micronized zeolites are used as detoxifying agents in humans. Detoxification is attributed to their ability to reduce lipid peroxidation by scavenging free radicals [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, Wu-Haan et al revealed that zeolites is a beneficial feed additive that exhibits a strong preference for binding nitrogenous cations like NH4 + and NH3 emission [ 17 ]. In this context, this substance was recommended to absorb various mycotoxins [ 13 , 18 ] to reduce ammonia production by pullets [ 17 ] and to remove ammonium from aqueous solutions [ 19 ], since the high atmospheric ammonia in poultry facilities might damage the respiratory tract lining, or even increased ascites and lower performance [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Does supplemental zeolite (clinoptilolite) affect growth performance, meat texture, oxidative stress and production of polyunsaturated fatty acid of Turkey poults?

et al. 2018

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BackgroundFollowing the ban on the use of growth factors, the use of zeolite in poultry feed could be a solution to obtain healthier food products that are more demanded by the consumer.MethodsZeolite (Clinoptilolite) was added to turkey male and female feed at concentrations 1% or 2% and was evaluated for its effectiveness on performance of the production. The turkeys were given free and continuous access to a nutritionally non-limiting diet (in meal form) that was either a basal diet or a ‘Zeolite supplemented-diet’ (the basal diet supplemented with clinoptilolite at a level of 1% or 2%).ResultsIt was found that adding zeolite in the turkey diet had a positive effect on growth performance and increased weight gain compared to the control. In addition, zeolite treatment had a positive effect on oxidative stress and organoleptic parameters that were measured. It was found that adding zeolite in the turkey diet reduced the MDA level in the liver and in the meat, as compared to the control. Quality of meat was measured as a significantly increase (p < 0.05) in pH for male meat, indicated that the zeolite could maintain the quality of longer period. The adding of zeolite in the turkey diet increased level of polyunsaturated fatty acid.ConclusionThis study showed the significance of using zeolite, as a feed additive for turkey, as part of a comprehensive program to improve growth performance and oxidative stress parameters and to increase level of polyunsaturated fatty acid on the turkey body.

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Section: Resultsmentioning

confidence: 99%

“…Activated and micronized zeolites are used as detoxifying agents in humans. Detoxification is attributed to their ability to reduce lipid peroxidation by scavenging free radicals [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Does supplemental zeolite (clinoptilolite) affect growth performance, meat texture, oxidative stress and production of polyunsaturated fatty acid of Turkey poults?

et al. 2018

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“…Thus, in healthy volunteers, in both a smoker and a non-smoker group, Dogliotti and colleagues demonstrated that natural zeolites, such as chabazite, phillipsite, and analcime, administered perorally for 4 weeks, increased the blood levels of gluthatione peroxidase, superoxide dismutase, and gluthatione reductase and reduced lipid peroxidation [ 224 ]. Next, in a randomized, double-blind clinical trial on smokers, it was further shown that micronized and activated natural zeolite increased catalase activity and decreased H 2 O 2 levels accompanied by a reduction in lipid peroxidation [ 225 ].…”

Section: Antioxidative Properties Of Zeolitementioning

confidence: 99%

Zeolite and Neurodegenerative Diseases

Panaiotov,

Tancheva,

Kalfin

et al. 2024

Molecules

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Neurodegenerative diseases (NDs), characterized by progressive degeneration and death of neurons, are strongly related to aging, and the number of people with NDs will continue to rise. Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the most common NDs, and the current treatments offer no cure. A growing body of research shows that AD and especially PD are intricately related to intestinal health and the gut microbiome and that both diseases can spread retrogradely from the gut to the brain. Zeolites are a large family of minerals built by [SiO4]4− and [AlO4]5− tetrahedrons joined by shared oxygen atoms and forming a three-dimensional microporous structure holding water molecules and ions. The most widespread and used zeolite is clinoptilolite, and additionally, mechanically activated clinoptilolites offer further improved beneficial effects. The current review describes and discusses the numerous positive effects of clinoptilolite and its forms on gut health and the gut microbiome, as well as their detoxifying, antioxidative, immunostimulatory, and anti-inflammatory effects, relevant to the treatment of NDs and especially AD and PD. The direct effects of clinoptilolite and its activated forms on AD pathology in vitro and in vivo are also reviewed, as well as the use of zeolites as biosensors and delivery systems related to PD.

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Role of Compositum Zeolite® in management of inflammatory bowel disease: a pilot study

Vernero

Leo

Givone

et al. 2020

Minerva Gastroenterol Dietol

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Activated and Micronized Zeolite in the Modulation of Cellular Oxidative Stress in Mexican Smokers: A Randomized Clinical Trial

Abstract: Background: Activated and micronized zeolites are used as detoxifying agents in humans. Detoxification is attributed to their

Cited by 5 publications

References 22 publications

Does supplemental zeolite (clinoptilolite) affect growth performance, meat texture, oxidative stress and production of polyunsaturated fatty acid of Turkey poults?

Does supplemental zeolite (clinoptilolite) affect growth performance, meat texture, oxidative stress and production of polyunsaturated fatty acid of Turkey poults?

Zeolite and Neurodegenerative Diseases

Role of Compositum Zeolite® in management of inflammatory bowel disease: a pilot study

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