Activated polymers. II: Synthesis and exchange reactions of biologically active poly(8-acryloxyquinoline)

Khalil, A. A.

doi:10.1007/s10965-012-0028-x

Cited by 6 publications

(1 citation statement)

References 24 publications

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“…By free radical polymerization, 8-acryloxyquinoline (8-AQ) monomer was prepared through the reaction of 8-hydroxyquinoline with either acryloyl chloride or acrylic acid in the presence of triethylamine or N, N-dicyclohexylcarbodiimide. The antimicrobial activity of all compounds demonstrated moderate to good activity against the tested strains providing wider possibilities for the synthesis of pharmacologically active polymers [8]. Improved polymerizations of monomers bearing electron transporting substituents based on 2,5-diphenyloxadiazole and 2,3-diphenylquinoxaline attached directly to a vinyl group were reported, these materials have been incorporated into light emitting polymer devices in which hole conduction properties are provided by 4-vinyltriphenylamine groups for usage in optimized devices [9].…”

Section: Introductionmentioning

confidence: 98%

Copolymerization of Quinazolinone Derivatives With Styrene, Methyl Methacrylate and Their Silver Nanocomposites for Biological Applications

El-Said¹,

El‐Barbary²,

ElKholy³

et al. 2021

Preprint

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Reaction of 2-mercapto-3-phenylquinazolin-4(3H)-one (MPQ) with both 4-vinyl benzyl chloride and allyl bromide furnished the reactive heterocyclic monomers 3-phenyl-2-((4-vinylbenzyl) thio) quinazolin-4(3H)-one (PVTQ) and 2-(allylthio)-3-phenylquinazolin-4(3H)-one (APQ), respectively. Copolymerization of PVTQ monomer with styrene and methyl methacrylate in the presence of 2,2′-azobisisobutyronitrile (AIBN) afforded the copolymers PS-co-PPVTQ and PMMA-co-PPVTQ, respectively. Similarly, copolymerization of monomer APQ with styrene and methyl methacrylate (MMA) afforded the copolymers PS-co-PAPQ and PMMA-co-PAPQ, respectively. The resulted copolymers were characterized by using FT-IR, 1H-NMR and GPC techniques. Silver nanocomposites of PS, PMMA, PS-co-PPVTQ, PMMA-co-PPVTQ, PS-co-PAPQ and PMMA-co-PAPQ were synthesized by the addition of silver nitrate into the polymer solution. The reduction of silver ions into silver nanoparticles was performed in DMF and water. Thermogravimetric (TGA) analysis was used to determine the thermal stability of the copolymers and their silver nanocomposites. The X-ray diffraction (XRD) analysis indicated the amorphous structures of the co-polymers and confirmed the formation of silver nanoparticles. The antitumor and antibacterial activities were screened for the copolymers and enhanced by the formation of their silver nanocomposites. In vivo antitumor activity in Ehrlich Ascitic Carcinoma (EAC) mice model showed that PS-co-PPVTQ/Ag NPs, PMMA-co-PPVTQ/Ag NPs, and PMMA-co-PAPQ/Ag NPs displayed promising inhibitory effects against EAC and induce apoptosis against MCF-7 cells.

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Section: Introductionmentioning

confidence: 98%

Copolymerization of Quinazolinone Derivatives With Styrene, Methyl Methacrylate and Their Silver Nanocomposites for Biological Applications

El-Said¹,

El‐Barbary²,

ElKholy³

et al. 2021

Preprint

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Synthetic Methodologies for Chelating Polymer Ligands: Recent Advances and Future Development

Джардималиева

Uflyand

2018

ChemistrySelect

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This review summarizes recent progress in synthetic methodologies of chelating polymer ligands such as linear, branched, cross‐linked, grafted polymers, polymer films, liquid crystal polymers, dendrimers, star‐shaped and hyperbranched polymers. The features of methods for producing chelating polymer ligands are considered in detail: free‐radical (co)polymerization, living/controlled radical, metathesis, grafted, chemical oxidized, microwave‐assisted and asymmetric polymerization, electropolymerization, cyclopolymerization, polycondensation, post‐polymerization modification, click chemistry methods and “green” synthesis. The main directions of the development of synthetic chemistry of chelating polymeric ligands are analyzed. The bibliography includes works published in the last five years.

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Polymer Chelating Ligands: Classification, Synthesis, Structure, and Chemical Transformations

Джардималиева

Uflyand

2018

Chemistry of Polymeric Metal Chelates

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Activated polymers. II: Synthesis and exchange reactions of biologically active poly(8-acryloxyquinoline)

Cited by 6 publications

References 24 publications

Copolymerization of Quinazolinone Derivatives With Styrene, Methyl Methacrylate and Their Silver Nanocomposites for Biological Applications

Copolymerization of Quinazolinone Derivatives With Styrene, Methyl Methacrylate and Their Silver Nanocomposites for Biological Applications

Synthetic Methodologies for Chelating Polymer Ligands: Recent Advances and Future Development

Polymer Chelating Ligands: Classification, Synthesis, Structure, and Chemical Transformations

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