Active and passive smoking, high-risk human papillomaviruses and cervical neoplasia

Coker, Ann L.; Bond, Sharon; Williams, Avis; Gerasimova, Tsilya; Pirisi, Lucia

doi:10.1016/s0361-090x(02)00039-9

Cited by 45 publications

(40 citation statements)

References 35 publications

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“…Our study demonstrated that there was an increased risk for SCCA in Thai females who had partners designated as current smokers and former .62-6.13, p=0.001] among Northeast Thai women. Some components of tobacco smoke-such as nicotine, cotinine, and benzo(α)pyrene can be detected in the cervical mucus (Simons et al, 1993;Prokopczyk et al, 1997;Coker et al, 2002). The possible routes of the components get access into the uterine cervix by inhalation and/or semen exposure (Kulikauskas et al, 1985;Perrin et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Cervical Cancer in Northeastern Thailand: Detailed Analyses of Sexual and Smoking Behavior

Natphopsuk

Settheetham-Ishida²,

Sinawat³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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Cervical cancer is a serious public health problem in Thailand. We investigated possible risk factors for cervical cancer including HPV infection, p53 polymorphism, smoking and reproductive history among women in Northeast Thailand using a case control study with 177 cases and age-matched controls. Among the HPV carriers, a significantly increased risk for cervical cancer with an OR of 36.97 (p<0.001) and an adjusted OR of 38.07 (p<0.001) were observed. Early age at first sexual exposure, and multiple sexual partners increased the risk of cervical cancer with ORs ranging between 1.73-2.78 (p<0.05). The interval between menarche and first sexual intercourse <6 years resulted in a significant increase in the risk for cervical cancer with ORs ranging between 3.32-4.09 and the respective adjusted OR range for the 4-5 and 2-3 year-old groups were 4.09 and 2.92. A higher risk was observed among subjects whose partner had smoking habits, whether currently or formerly; with respective ORs of 3.36 (p<0.001) and 2.17 (p<0.05); and respective adjusted ORs of 2.90 (p<0.05) and 3.55 (p<0.05). Other smoking characteristics of the partners including smoking duration ≥ 20 years, number of cigarettes smokes ≥ 20 pack-years and exposure time of the subject to passive smoking ≥ 5 hrs per day were found to be statistically significant risks for cervical cancer with adjusted ORs of 3.75, 4.04 and 11.8, respectively. Our data suggest that the risk of cervical cancer in Thai women is substantially associated with smoking characteristics of the partner(s), the interval between menarche and first sexual intercourse as well as some other aspects of sexual behavior.

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Section: Discussionmentioning

confidence: 99%

Risk Factors for Cervical Cancer in Northeastern Thailand: Detailed Analyses of Sexual and Smoking Behavior

Natphopsuk

Settheetham-Ishida²,

Sinawat³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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“…A total of 10 new studies have been identified: one cohort study (Table 2.11 available at http://monographs.iarc.fr/ENG/Monographs/ vol100E/100E-02-Table2.11.pdf) and nine casecontrol studies (Buckley et al, 1981;Brown et al, 1982;Hellberg et al, 1986;Hirose et al, 1996;Coker et al, 2002;Wu et al, 2003;Tay & Tay, 2004;Sobti et al, 2006;Tsai et al, 2007;Table 2.12 available at http://monographs.iarc.fr/ ENG/Monographs/vol100E/100E-02-Table2.12. pdf).…”

Section: Cancer Of the Cervixmentioning

confidence: 99%

“…A later study (Coker et al, 2002) looked at risk of low grade and high grade cervical squamous intraepithelial lesions (LSIL and HSIL, respectively) in HPV positive never-smokers and reported a significant association with exposure to secondhand tobacco smoke. In a community-based case-control study, Tsai et al (2007) observed a markedly increased risk for both CIN1 and CIN2 in both HPV-positive and HPV-negative women exposed to second-hand tobacco smoke.…”

Section: (B) Cervical Intraepithelial Lesions and Neoplasiamentioning

confidence: 99%

“…In a community-based case-control study, Tsai et al (2007) observed a markedly increased risk for both CIN1 and CIN2 in both HPV-positive and HPV-negative women exposed to second-hand tobacco smoke. Only Coker et al (2002) and Tsai et al (2007) controlled for HPV status in women. Sobti et al (2006) reported that cervical cancer risk is increased in individuals exposed to second-hand tobacco smoke with GSTM1 (null), GSTT1 (null) and GSTP1 (Ile 105 Val) genotypes, with odd ratios ranging from 6.4 to 10.2.…”

Section: (B) Cervical Intraepithelial Lesions and Neoplasiamentioning

confidence: 99%

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Secondhand Tobacco Smoke

2011

Encyclopedia of Cancer

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“…Tobacco usage rate reported among premenopausal study subjects by Moore et al was 49%, and 36% among menopausal women, in their study of 359 women presenting to the colposcopy clinic. 39 Coker et al (2002) 121 reported the following smoking rates among women with HSIL cytology results: 36% reported that they had ever smoked, with 31% currently smoking and 5% former smokers. Women with LSIL Pap results reported having ever smoked 34% of the time, while 24% currently smoked, and 9% were former smokers.…”

Section: Smoking Statusmentioning

confidence: 99%

The Effect of Progesterone Only Contraception on the Accuracy of Cervical Cytologic interpretation

Collins¹

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Active and passive smoking, high-risk human papillomaviruses and cervical neoplasia

Cited by 45 publications

References 35 publications

Risk Factors for Cervical Cancer in Northeastern Thailand: Detailed Analyses of Sexual and Smoking Behavior

Risk Factors for Cervical Cancer in Northeastern Thailand: Detailed Analyses of Sexual and Smoking Behavior

Secondhand Tobacco Smoke

The Effect of Progesterone Only Contraception on the Accuracy of Cervical Cytologic interpretation

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