Activities and concentration of alpha-1 antitrypsin and cystatin C in serum from patients with house dust mite asthma
Mailani Dwi Hidayati,
Febriana Catur Iswanti,
Samsuridjal Djauzi
et al.
Abstract:Background:
The proteolytic activities of house dust mite (HDM) allergens are involved in the pathogenesis of asthma by cleaving T-junction protein complexes, increasing the permeability of airway epithelial cells, and enabling the allergens to reach the interstitial tissue. The human body contains natural protease inhibitors such as alpha-1 antitrypsin (AAT) with antiserine protease activity and cystatin C with anticysteine protease activity.
Objective:
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