Activity of α- and β-mannosidases in semen and reproductive organs of the drake

Dżugan, Małgorzata; Ksiazkiewicz, J.

doi:10.1016/s1642-431x(12)60092-8

Cited by 5 publications

(3 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Observations of bleeding in the interstitium are likely to reduce the testosterone production in Leydig cells, which decreases male fertility. [12,13] This damage, however, was only temporary and disappeared after some time due to bendiocarb excretion from the body and testes recovering. This confirms the claim of Mojzisova and Sulla, [14] which states that carbamates leave residues only slightly.…”

Section: Discussionmentioning

confidence: 99%

In vivoandin vitroeffect of bendiocarb on rabbit testicular structure and spermatozoa motility

Kročková

Massányi

Toman

et al. 2012

Journal of Environmental Science and Health, Part A

View full text Add to dashboard Cite

In this study the effect of bendiocarb on the rabbit testicular structure and spermatozoa motility was investigated. For testicular structure evaluation the animals were fed with bendiocarb tablets daily at a dose of 5 mg/kg of body weight for 13 days. The relative volume of the germinal epithelium, interstitium and lumen was measured. The testicular structure evaluation showed decreased relative volume of germinal epithelium in both experimental groups in comparison with the control group. The relative volume of the interstitium was increased in both experimental groups. An increase of the relative volume of the lumen was registered also in both experimental groups. Qualitative analysis detected a dilatation of blood vessels in the interstitium, undulation of the basal membrane and some empty spaces in the germinal epithelium after bendiocarb administration. The spermatozoa motility was evaluated by the computer assisted semen analyzer (CASA) method in various time intervals (0-180 minutes) and the bendiocarb concentration in the culture medium added to experimental groups varied from 0.054 to 0.268 mg/mL. Spermatozoa motility and progressive motility significantly decreased with increased bendiocarb administration and with extending the period of incubation. For other fine motility parameters, a decrease dependent on the time of incubation and on the bendiocarb concentration almost in all experimental groups in comparison to the control was detected. These results clearly suggest that in vitro also in vivo bendiocarb administration decrease male fertility.

show abstract

Section: Discussionmentioning

confidence: 99%

In vivoandin vitroeffect of bendiocarb on rabbit testicular structure and spermatozoa motility

Kročková

Massányi

Toman

et al. 2012

Journal of Environmental Science and Health, Part A

View full text Add to dashboard Cite

show abstract

“…TPPP family members play a role in maintaining the integrity of microtubules in ciliated cells, including neurons and sperm cells, suggesting a possible involvement in sperm tail stabilization ( 11 ). Mannosidase, an enzyme originating from the epididymis, is found in the seminal plasma of various species ( 7 , 57 , 58 ), including Asian elephants. Mannosidase is also presented on the sperm membrane and is involved in sperm-egg fertilization ( 11 ).…”

Section: Discussionmentioning

confidence: 99%

Non-targeted proteomic analysis of Asian elephant (Elephas maximus) seminal plasma using an in-solution digestion technique and liquid chromatography tandem-mass spectrometry

Wattananit,

Yingchutrakul,

Kornkaewrat

et al. 2023

Front. Vet. Sci.

View full text Add to dashboard Cite

Seminal plasma proteins have recently been reported to play a significant role as valuable materials for understanding male reproductive biology, identifying causes of fertility problems, and developing reproductive biomarkers. Proteomic analysis of seminal plasma holds promise in advancing the understanding of male Asian elephant reproductive biology. This study aims to explore seminal plasma proteins of Asian elephants and their probable functions to provide fundamental information about male reproduction in this species. The protein solution from pooled seminal plasma from 10 bulls (a total of 33 ejaculates) was digested into peptides and identified using LC-MS/MS. Out of 986 proteins, 597 were mapped and matched with 58 species in UniProt databases, including Elephas maximus. These mapped proteins were mostly involved in binding function, catalytic activity, cellular process, and metabolic process. Only 29 mapped proteins were recognized to be related in reproductive process, mainly associated in spermatogenesis and sperm capacitation. Additionally, several seminal plasma proteins related to fertility or semen quality in other mammals were also found in Asian elephant semen, such as keratin type I, aldose reductase, thrombospondon-1, fibronectin 1, platelet-activating factor acetyl hydrolase, mannosidase, and semenogelin-2. This discovery clearly reveals the beneficial protein profile in seminal plasma of the Asian elephant and serves as a crucial step in investigating infertility and poor semen quality in this valuable species.

show abstract

“…Moreover, α-mannosidase is one of the lysosomal glycosidases in mammals’ male genital tract and semen. Mannosidases are associated mainly with reproductive and Sertoli cells and play a significant role in spermatozoa maturation [ 87 ]. Moreover, α-mannosidase is implicated as a non-catalytic binding protein during sperm-oocyte interaction.…”

Section: Discussionmentioning

confidence: 99%

The Synergetic Effect of Egyptian Portulaca oleracea L. (Purslane) and Cichorium intybus L. (Chicory) Extracts against Glucocorticoid-Induced Testicular Toxicity in Rats through Attenuation of Oxidative Reactions and Autophagy

et al. 2022

View full text Add to dashboard Cite

Long-term glucocorticoids can alter sperm motility, vitality, or morphology, disrupting male reproductive function. This study scrutinized the synergistic benefits of two Egyptian plants against dexamethasone (Dexa)-induced testicular and autophagy dysfunction in male rats. Phytochemical ingredients and the combination index were estimated for Purslane ethanolic extract (PEE) and Chicory water extract (CWE). Four control groups received saline and 100 mg/kg of each PEE, CWE, and PEE/CWE, daily for 8 weeks. Dexa (1 mg/kg daily for 6 weeks) induced infertility where PEE, CWE, and PEE/CWE were given. Seminal analysis, male hormones, glycemic and oxidative stress markers, endoplasmic reticulum (ER) stress markers (Sigma 1R and GRP78), and autophagy regulators (Phospho-mTOR, LC3I/II, PI3KC3, and Beclin-1, P62, ATG5, and ATG7) were measured. The in vitro study illustrated the synergistic (CI < 1) antioxidant capacity of the PEE/CWE combination. Dexa exerts testicular damage by inducing oxidative reactions, a marked reduction in serum testosterone, TSH and LH levels, insulin resistance, ER stress, and autophagy. In contrast, the PEE and CWE extracts improve fertility hormones, sperm motility, and testicular histological alterations through attenuating oxidative stress and autophagy, with a synergistic effect upon combination. In conclusion, the administration of PEE/CWE has promised ameliorative impacts on male infertility and can delay disease progression.

show abstract

Activity of α- and β-mannosidases in semen and reproductive organs of the drake

Cited by 5 publications

References 19 publications

In vivoandin vitroeffect of bendiocarb on rabbit testicular structure and spermatozoa motility

In vivoandin vitroeffect of bendiocarb on rabbit testicular structure and spermatozoa motility

Non-targeted proteomic analysis of Asian elephant (Elephas maximus) seminal plasma using an in-solution digestion technique and liquid chromatography tandem-mass spectrometry

The Synergetic Effect of Egyptian Portulaca oleracea L. (Purslane) and Cichorium intybus L. (Chicory) Extracts against Glucocorticoid-Induced Testicular Toxicity in Rats through Attenuation of Oxidative Reactions and Autophagy

Contact Info

Product

Resources

About