Acute appendicitis presenting with MIS-C secondary to COVID-19

Sturgill, Amanda; Cannon, Rachael; Patel, Shivani A.; Horbey, Andrea; Chua, Raymond; Souffrant, Dilsa; Davenport, Stephanie

doi:10.1016/j.epsc.2022.102380

Cited by 2 publications

(1 citation statement)

References 2 publications

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“…In the present case, the findings resulted in a clinical suspicion of AA with subsequent surgery. As in the present case, Sturgill et al 21 presented a series of three children diagnosed with appendicitis and MIS-C related to SARS-CoV-2; all patients were initially admitted with a diagnosis of appendicitis and had an appendectomy before the further diagnosis of MIS-C. One and two cases from two-case series reported from South Africa and Indonesia, respectively, were treated nonsurgically and only received systemic antibiotics and antiviral medication. 22,23 Tullie et al 24 presented a case series and highlighted that children with MIS-C associated with COVID-19 may exhibit clinical characteristics suggesting appendicitis.…”

Section: Discussionmentioning

confidence: 69%

Coincidental or mimicking acute appendicitis secondary to MIS-C associated with SARS-CoV-2: A case report

Ramosaj-Morina

Keka-Sylaj

Baloku

et al. 2023

SAGE Open Medical Case Reports

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The predominant organic system involved in multisystem inflammatory syndrome in children associated with COVID-19 is the gastrointestinal system, which is observed in almost 90% of patients. Gastrointestinal symptoms can mimic acute appendicitis. There have been a few cases of misdiagnosed multisystem inflammatory syndrome in children associated with SARS-CoV-2 as appendicitis, and a few concomitant cases of a multisystem inflammatory syndrome associated with acute appendicitis during the COVID-19 pandemic. Here, we present the case of an 11-year-old girl who presented to our Intensive Care Unit with a 2-day history of fever, generalized abdominal pain, and vomiting. The clinical findings resulted in a clinical suspicion of acute appendicitis and subsequent surgery. While postoperatively, she became critically ill, and she was diagnosed with the multisystem inflammatory syndrome in children associated with COVID-19. When diagnosing children with acute appendicitis, healthcare professionals, especially pediatricians and surgeons, must pay attention to the multisystem inflammatory syndrome linked to the SARS-CoV-2 infection.

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Section: Discussionmentioning

confidence: 69%

Coincidental or mimicking acute appendicitis secondary to MIS-C associated with SARS-CoV-2: A case report

Ramosaj-Morina

Keka-Sylaj

Baloku

et al. 2023

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

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COVID19 detection in appendix of acute appendicitis in a child: a case report and review of literature

et al. 2023

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Background Gastrointestinal symptoms are one of the most common presentations of Coronavirus disease-19 (COVID-19), even in children. Higher rates of complicated appendicitis have been demonstrated in the era of the COVID-19 outbreak, and it has been recently suggested that acute appendicitis may occur as a complication of COVID-19. However, the relationship between appendicitis and COVID-19 remains unclear. Case presentation A 7-year-old male presented to the pediatric emergency department with 2 days’ history of lower abdominal discomfort and tenderness. On examination, his abdomen was distended with diffuse mild tenderness at the lower abdomen, which was aggravated by movement. He was also tested and was found to be positive for SARS-CoV-2. Computed tomography showed perforated appendicitis with a fecalith. The patient was admitted and laparoscopic appendectomy was successfully performed. Postoperatively, a minor intra-abdominal abscess was present, which successfully treated with antibiotics. Histopathology showed a markedly inflamed appendix with mucosal ulceration and transmural neutrophilic inflammation, which was consistent with phlegmonous appendicitis. Reverse transcription quantitative polymerase chain reaction using a surgically extracted appendix specimen revealed the presence of SARS-CoV-2 virus, which indicated a pathophysiological relationship between appendicitis and COVID-19. Conclusion The present case will provide further understanding of pediatric patients with concomitant COVID-19 and acute appendicitis.

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Acute appendicitis presenting with MIS-C secondary to COVID-19

Cited by 2 publications

References 2 publications

Coincidental or mimicking acute appendicitis secondary to MIS-C associated with SARS-CoV-2: A case report

Coincidental or mimicking acute appendicitis secondary to MIS-C associated with SARS-CoV-2: A case report

COVID19 detection in appendix of acute appendicitis in a child: a case report and review of literature

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